Results 191 to 200 of about 1,139,706 (263)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

It's not just what you have, but when: The role and timing of developmental assets in the mental health of young adults. [PDF]

J Res Adolesc
Morneau-Vaillancourt G, Thibault M, Bilodeau-Houle A, Comtois-Cabana M, Boivin M, Côté S, Geoffroy MC, Matte-Landry A, Ouellet-Morin I.   +8 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

A second locus associated with high-level resistance to Bt Cry1Ac in <i>Trichoplusia ni</i>. [PDF]

Appl Environ Microbiol
Yang X, Cotto-Rivera RO, Fei Z, Wang P.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Longitudinal data improves selection of drought-tolerant Eucalyptus germplasm. [PDF]

Sci Rep
Canal GB, Dos Santos GA, Ferreira FM, Bhering LL, Nogueira TAPC, Paixão CF, Chaves S, Dias KOG.   +7 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

The P450 EcCYP89B16 broadens the metabolic landscape of herbicide resistance in barnyardgrass (Echinochloa crus-galli). [PDF]

Plant Physiol
Khatri P.
europepmc   +1 more source

Pan-genome landscape of the JAZ family in pepper (<i>Capsicum annuum</i> L.): core-variable architecture and hormone crosstalk in leaves. [PDF]

Front Plant Sci
Zhong H, Song X, Chen Q, Wang L, Guo J, Wang B, Xie Z, Niu T, Shi J, Tang M, Yang J.   +10 more
europepmc   +1 more source