Results 101 to 110 of about 3,977,981 (306)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Cancer Patients’ Views on the Family Changes and the Family Social Support
Journal of European Psychology Students, 2018 When someone is diagnosed with cancer, their entire family is affected. This study investigates how patients with cancer perceive changes in their family and the types of support provided by family members.
Nikolaos Vrontaras
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Who Dies Alone? Demographics, Underlying Diseases, and Healthcare Utilization Patterns of Lonely Death Individuals in Korea [PDF]
Journal of Preventive Medicine and Public HealthObjectives Lonely death is defined as “a person living in a state of social isolation, disconnected from family, relatives, and others, who dies from suicide, illness, or other causes”.
Haibin Bai +8 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Hubungan dukungan keluarga dan keberfungsian sosial pada pasien skizofrenia rawat jalan
Jurnal Ilmiah Psikologi Terapan, 2016 Social functioning of an individual's is an ability to implement its duties an role during interact in certain social situations. The ability of the individual as a member of the family in social functioning positively and adaptively may reflect how ...
Fauziah Sefrina
doaj +1 more source
Hubungan Antara Dukungan Keluarga Dengan Respon Sosial Pada Lansia Di Desa Sokaraja Lor Kecamatan Sokaraja [PDF]
, 2010 Generally, the physical condition after entering elderly period is experienced decreasing. Changes in elderly generally directed to physical and psychics healthy decreasing and finally will influence on their economic and social activity.
Nusi, F. (Ferani) +2 more
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source