Results 141 to 150 of about 3,977,981 (306)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Polysubstance use among frequent marijuana users: an examination of John Henryism Active Coping, psychiatric symptoms, and family social support among African American incarcerated men. [PDF]
Wheeler PB +3 more
europepmc +1 more source
How has internal migration in Albania affected the receipt of transfers from family and friends? [PDF]
Social networks of family and friends are very important in providing economic and social support to households. The massive internal migration flows towards the big cities in the transition countries like Albania can seriously affect such networks, and ...
Hagen-Zanker, Jessica, Tomini, Florian
core +1 more source
Social Interaction and Intergenerational Skill Transfer [PDF]
We explore the relationship between educational attainment and social interaction using individual level data from the British National Child Development Study. To be specific, we analyze whether an intergenerational aspect to this relationship exists by
Brown, S., Taylor, K.
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
This chapter focuses on a specific type of transgender family, where one of the parents has come out as being transgender. It discusses the characteristics of these families, as well as some of the difficulties transgender families encounter following ...
Dierckx, Myrte +2 more
core
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Exploring support and coping mechanisms for tribal infertility: A mixed methods study
Objective: The study explores the support mechanisms and coping strategies used by 153 tribal couples to navigate infertility. Methods: The data was collected through quantitative and qualitative surveys and analyzed using descriptive and thematic ...
Arvind Santu Jadhav, Dipti Govil
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source

