Results 141 to 150 of about 3,977,981 (306)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

How has internal migration in Albania affected the receipt of transfers from family and friends? [PDF]

open access: yes
Social networks of family and friends are very important in providing economic and social support to households. The massive internal migration flows towards the big cities in the transition countries like Albania can seriously affect such networks, and ...
Hagen-Zanker, Jessica, Tomini, Florian
core   +1 more source

Social Interaction and Intergenerational Skill Transfer [PDF]

open access: yes, 2006
We explore the relationship between educational attainment and social interaction using individual level data from the British National Child Development Study. To be specific, we analyze whether an intergenerational aspect to this relationship exists by
Brown, S., Taylor, K.
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Transgender families [PDF]

open access: yes, 2017
This chapter focuses on a specific type of transgender family, where one of the parents has come out as being transgender. It discusses the characteristics of these families, as well as some of the difficulties transgender families encounter following ...
Dierckx, Myrte   +2 more
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Exploring support and coping mechanisms for tribal infertility: A mixed methods study

open access: yesClinical Epidemiology and Global Health
Objective: The study explores the support mechanisms and coping strategies used by 153 tribal couples to navigate infertility. Methods: The data was collected through quantitative and qualitative surveys and analyzed using descriptive and thematic ...
Arvind Santu Jadhav, Dipti Govil
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

The relationship between family socio-economic status, family social support and adolescent physical activity

open access: yesHealth Problems of Civilization, 2019
Hrvoje Ajman, Marita Ukić, Dejan Madić
doaj   +1 more source

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