Results 101 to 110 of about 3,118,114 (313)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Good practice guidelines for peer led family support groups.
, 2010 1. Introduction 2. Starting a peer led family support group 3. Providing support in a group 4. Facilitation 5. Seeking external support 6. Setting up a family support network Appendix A: Governance Appendix B: Steering group members Appendix C ...
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Review of government initiatives for reconciling work and family life [PDF]
, 2015 Presents a review of government initiatives that help families balance their work and family responsibilities, highlighting innovative ideas and including a discussion of international trends and themes. Summary This AIFS Research Report presents a
Jennifer Baxter, Jennifer Renda
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Frontiers in PediatricsAs the lifespan of cystinosis patients extends, mental health issues increasingly impact both patients and their caregivers. The emotional journey for patients and “raregivers” has been mapped, providing a valuable guide across a patient's lifetime ...
Maya H. Doyle, Chelsea Meschke
doaj +1 more source
, 2010 This study examined the relationship between family-focused organisational and .supervisor support and the positive work outcomes, job satisfaction, affective commitment, continuous commitment and work-family ...
Mohasi, Mapalo
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The effect of prolonged support group attendance on depression among family caregivers to patients with dementia [PDF]
, 1999 Plan BDecreasing mortality rates and increasing life expectancy are contributing factors in the population growth of those 65 and older. This is of particular importance because research indicates as humans age the probability of developing a dementing ...
Elliott, Ryan M.
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Family Services programs (2017)
, 2017 Rev. 6/17.; Cover title.; "JDP-FM-211.
Connecticut. Court Support Services Division. Family Services,
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