Results 51 to 60 of about 2,448,036 (303)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Psychiatric disorders endorsed by trauma-exposed premenopausal women enrolled in a cardiovascular research study: a 2-year report

Discover Mental Health
Introduction Women are more likely than men to experience interpersonal trauma, with 1 in 3 women affected globally. This paper aims to give a 2-year report of the demographics, trauma history [i.e., non-interpersonal and interpersonal including adverse ...
Chowdhury Tasnova Tahsin, Zynab Ahmed, Azhaar Mohamed, Chowdhury Ibtida Tahmin, Redeat Wattero, Chasity Corbin, Ida T. Fonkoue   +6 more
doaj   +1 more source

Combat Related Post Traumatic Stress Disorder in Veterans of Operation Enduring Freedom and Operation Iraqi Freedom: A Review of the Literature [PDF]

, 2012
The conflict Afghanistan and Iraq have now taken their places amongst the longest running wars in American history. As many Americans return from military service, the prevalence of combat related post traumatic stress syndrome is estimated to be as high
Kaiser, Dakota J
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Clergy Wives and Well-Being: The Impact of Perceived Congregational Perfectionism and Protective Factors

Religions
Clergy wives often face high congregational expectations that impact their psychological well-being. This study investigates the impact of perceived congregational perfectionism on the psychological well-being of 215 Asian clergy wives and explores the ...
Ching-Ying Lin, Kenneth T. Wang
doaj   +1 more source

Family therapy in India

Annals of Indian Psychiatry, 2018
Origins of family therapy are traced, acknowledging that this is in fact a group of therapeutic approaches. An overview of work done at major mental health centers in India is followed by an attempt at outlining key differences in Indian vis-a-vis ...
Anuradha Vishwas Sovani
doaj   +1 more source

The use of interpretive phenomenological analysis in couple and family therapy research [PDF]

, 2016
This article proposes a research methodology that is newer to the field of couple and family therapy research called Interpretive Phenomenological Analysis (IPA).
Bromley D. B., Creswell J. W., Dahl C. M., Falicov C. J., Falicov C. J., Gadamer H.-G., Geertz C., Giorgi A., Holloway I., Krell D. F., Lebow J., Maxwell J. A., McCandless R., Merleau-Ponty M., Palmer R., Reid K., Robert Allan, Sartre J.-P., Sayer A., Sexton T. L., Shaw R. L., Smith J. A., Smith J. A., Smith J. A., Sprenkle D. H., Ungar M., Virginia Eatough, Willig C., Zahavi D.   +28 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Parenting Stress in Mothers of Mentally Retarded, Blind, Deaf and Physically Disabled Children

Salāmat-i ijtimā̒ī, 2017
Background and Objective: Parents of children with disabilities are poorer physical and mental health and greater stress experience. This study was conducted to evaluate Parenting stress in mothers of mentally retarded, blind, deaf and physically ...
Mohammad Kazem Atefvahid, Mojtaba Habibi Asgarabad, Ahmad Ashouri, Sayed Hadi Sayed Alitabar   +3 more
doaj  

Tracing the storyline from parent to child : insights into improved family therapy : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education in Guidance Counselling at Massey University, Palmerston North, New Zealand [PDF]

, 2000
The effects of the application of attachment theory and classification measurements to family therapy was examined in order to judge its contribution to family therapy.
Fisch, Marta Lynne
core