Results 61 to 70 of about 2,448,036 (303)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The temporal association between religious/spiritual struggles and anxiety symptoms: A longitudinal study of psychiatric outpatients

open access: yesJournal of Affective Disorders Reports
Background: Anxiety disorders like Generalized Anxiety Disorder (GAD) often cooccur with religious/spiritual (R/S) struggles, but the temporal association between anxiety symptoms and R/S struggles has not been studied in many clinical samples.
Curtis Beeman   +11 more
doaj   +1 more source

Comparison of Family Awareness, Emotional Climate, and Emotional Divorce among Married Men and Women in Yazd [PDF]

open access: yesJournal of Social Behavior and Community Health, 2023
Background: This research was conducted with the aim of comparing family awareness, emotional climate, and emotional divorce among married men and women in Yazd.
Atefeh Ahmadi Sanori   +3 more
doaj  

‘She needs a smack in the gob’: negotiating what is appropriate talk in front of children in family therapy [PDF]

open access: yes, 2012
This is the peer reviewed version of the following article: O'Reilly, M., & Parker, N. (2014). ‘She needs a smack in the gob’: negotiating what is appropriate talk in front of children in family therapy. Journal of Family Therapy, 36(3), 287-307. https://
O'Reilly, Michelle, Parker, Nicola
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Exoskeleton Rehabilitation for Complete Thoracic Spinal Cord Lesion: A Case Study

open access: yesDisabilities
Background: Spinal cord injury is a life-changing condition for individuals who have previously been independent in activities of daily living. Motor recovery prognosis for individuals with complete spinal cord lesion above thoracic level ten is poor ...
Rina Xue Li Choo   +3 more
doaj   +1 more source

The impact of gambling problems on families [PDF]

open access: yes, 2014
Summarises the available research about how gambling problems affect family relationships and family members, how families cope with gambling problems, and the assessment and therapy options available to the family members of people with gambling ...
Nicki Dowling
core  

Progress in the use of adeno-associated viral vectors for gene therapy [PDF]

open access: yes, 2004
The development of safe and efficient gene transfer vectors is crucial for the success of gene therapy trials. A viral vector system promising to meet these requirements is based on the apathogenic adeno-associated virus (AAV-2), a member of the ...
Braun-Falco, M., Buning, H., Hallek, M.
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

A pragmatic randomised controlled trial and economic evaluation of family therapy versus treatment as usual for young people seen after second or subsequent episodes of self-harm: the Self-Harm Intervention – Family Therapy (SHIFT) trial

open access: yesHealth Technology Assessment, 2018
Background: Self-harm in adolescents is common and repetition rates high. There is limited evidence of the effectiveness of interventions to reduce self-harm.
David J Cottrell   +14 more
doaj   +1 more source

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