Results 71 to 80 of about 2,448,036 (303)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Family orientation group as a strategy for care in chemical codependency
Investigación y Educación en Enfermería, 2019 Objective. To determine the importance of the family support group in the treatment of codependency, based in reports made by relatives of a therapeutic community for drug addicts. Methods.
Michele Peixoto da Silva +4 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
From Undereating to Overeating: Family Survival Strategies and Their Consequences
Психология и Психотерапия СемьиThe article provides an overview of the multigenerational transmission process of eating behaviors and habits in Russia. During the mass hunger and food shortages in the 20th century people in Russia learned certain dietary patterns and food psychology ...
Kseniya Novgorodova
doaj +1 more source
Clients\u27 Experiences Giving Gifts to Therapists [PDF]
, 2009 Nine therapy clients were interviewed regarding their experiences of giving gifts to therapists. Data were analyzed using consensual qualitative research.
Dubois, Robert +4 more
core +1 more source
Systemic family therapy and the elderly: contributions and challenges [PDF]
, 2008 O presente artigo descreve algumas intervenções clínicas de orientação sistêmica que podem ser realizadas com a população idosa. Quatro modalidades terapêuticas são abordadas: a terapia individual com idosos, a terapia de casal na terceira idade, o ...
COUTO, Maria Clara P. de Paula +3 more
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Pengaruh Psikoedukasi Keluarga Terhadap Kemampuan Keluarga Dalam Merawat Klien Isolasi Sosial [PDF]
, 2010 Social isolation is an individual failure in the interaction with other people because of negative thinking or threatening.The purpose of this study to determine the effect of family psycho education therapy toward family's ability on caring of client ...
Wahyuningsih, D. (Dyah) +2 more
core
Could Upregulated Hsp70 Protein Compensate for the Hsp90-Silence-Induced Cell Death in Glioma Cells? [PDF]
, 2014 The molecular chaperone heat shock protein 90 alpha (Hsp90α) has been recognized in various tumours including glioma. This pilot study using a proteomic approach analyses the downstream effects of Hsp90 inhibition using 17-allylamino-17 ...
Khan, Zarine Jamsher +3 more
core +2 more sources