Results 91 to 100 of about 9,981,389 (290)
W niniejszym artykule podjęta została próba zarysu problemu wartości i wartościowania z metodologicznej perspektywy pedagogiki rodziny. Problematykę tę można ująć umownie w odwołaniu do wstępnych ustaleń, do ogólnych ujęć na temat udziału aksjologii w ...
Danuta Opozda
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Family medicine : present and future
Contents: Future prospects of the College - Pierre Mallia; The contemporary College and Council - Jason J Bonnici; Immersion pulmonary oedema in a scuba diver - Mario Saliba; eHealth and mHealth - bridging gaps in health care - Martina FalzonThe ...
Mallia, Pierre +2 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Testing the Efficacy of Family Health-Model of REBT on Family Values and Quality of Family Life Among Parents of Children with Visual Impairment. [PDF]
Ede MO +4 more
europepmc +1 more source
The article shows how Russian students assess the role of the university as a socialization institution in strengthening the value of family and in their preparing for marriage, birth and raising children.
I. E. Strelets +2 more
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MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
The article deals with methodological approaches to a problem of classification of family values. Authors provide a classification of family values structure from medical and social positions: material values (money, financial position, living conditions)
Tatiana Vladimirovna Anafianova +2 more
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Forms of Social Capital in the Romanian Kinship [PDF]
This study aims at providing a theoretical and methodological preamble to the more ample issue concerning the research project entitled „Modele de interacţiune între capitalul social informal şi formal; investigarea rolului de suport şi mediator al ...
PETRU ILUŢ
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