Results 81 to 90 of about 2,075,944 (253)
Family leisure facilities as a driver of city development
Urbis et Orbis: Mikroistoriâ i Semiotika GorodaThe study examines the issue of developing family leisure facilities within the context of urban space management. The relevance of this problem lies in research indicating that families engaged in family leisure activities tend to be stronger ...
Oksana Gomazova +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Testing the Efficacy of Family Health-Model of REBT on Family Values and Quality of Family Life Among Parents of Children with Visual Impairment. [PDF]
J Ration Emot Cogn Behav Ther, 2022 Ede MO +4 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
RUDN journal of SociologyThe article shows how Russian students assess the role of the university as a socialization institution in strengthening the value of family and in their preparing for marriage, birth and raising children.
I. E. Strelets +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Sovremennye Issledovaniâ Socialʹnyh Problem, 2013 The article deals with methodological approaches to a problem of classification of family values. Authors provide a classification of family values structure from medical and social positions: material values (money, financial position, living conditions)
Tatiana Vladimirovna Anafianova +2 more
doaj
Forms of Social Capital in the Romanian Kinship [PDF]
Revista Română de Sociologie, 2010 This study aims at providing a theoretical and methodological preamble to the more ample issue concerning the research project entitled „Modele de interacţiune între capitalul social informal şi formal; investigarea rolului de suport şi mediator al ...
PETRU ILUŢ
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source