The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Genetic Evaluation and Selection of <i>Eucalyptus urophylla</i> Families and Hybrids for Cold Tolerance in Northern Guangdong, South China. [PDF]
Zhu M +10 more
europepmc +1 more source
Development and validation of the Behavioral FAmily Sport SupporT (BFaSST) Scale. [PDF]
Hernandez A +3 more
europepmc +1 more source
Health-Promoting Lifestyle and Psychosocial Correlates in Patients with NAFLD/MASLD and Family Members: A Comparative Cross-Sectional Study of Independent Samples. [PDF]
Yu Y, Ji L.
europepmc +1 more source
A Retrospective Study of the Career Decision-Making of Young Adults Who Participated in the PSMIGP Program for Gifted Preschoolers. [PDF]
Yu CH, Kuo CC.
europepmc +1 more source
Exogenous Polyamines and Plant Salinity Tolerance: A Systematic Review, Evidence Map, and Family-Aware Quantitative Synthesis. [PDF]
Ribeiro JEDS +8 more
europepmc +1 more source

