Results 91 to 100 of about 9,991,757 (291)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Family medicine : present and future
, 2013 Contents: Future prospects of the College - Pierre Mallia; The contemporary College and Council - Jason J Bonnici; Immersion pulmonary oedema in a scuba diver - Mario Saliba; eHealth and mHealth - bridging gaps in health care - Martina FalzonThe ...
Mallia, Pierre +2 more
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Testing the Efficacy of Family Health-Model of REBT on Family Values and Quality of Family Life Among Parents of Children with Visual Impairment. [PDF]
J Ration Emot Cogn Behav Ther, 2022 Ede MO +4 more
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
RUDN journal of SociologyThe article shows how Russian students assess the role of the university as a socialization institution in strengthening the value of family and in their preparing for marriage, birth and raising children.
I. E. Strelets +2 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Sovremennye Issledovaniâ Socialʹnyh Problem, 2013 The article deals with methodological approaches to a problem of classification of family values. Authors provide a classification of family values structure from medical and social positions: material values (money, financial position, living conditions)
Tatiana Vladimirovna Anafianova +2 more
doaj
Forms of Social Capital in the Romanian Kinship [PDF]
Revista Română de Sociologie, 2010 This study aims at providing a theoretical and methodological preamble to the more ample issue concerning the research project entitled „Modele de interacţiune între capitalul social informal şi formal; investigarea rolului de suport şi mediator al ...
PETRU ILUŢ
doaj
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source