Results 71 to 80 of about 9,981,389 (290)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Values and longevity in family business: Evidence from a cross-cultural analysis [PDF]
The link between longevity and values has been pointed out by several authors, who have underlined values as an important factor for supporting a long-term vision, as well as a source of competitive advantage based on using values as specific company ...
Fernandez, Maria, Tapies, Josep
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Impact of globalization on Islamic family values [PDF]
Globalization, characterized by the rapid exchange of ideas, culture, and economic practices across borders, has significantly impacted various aspects of life, including family values. In the context of Islamic family values, globalization presents both
Karim, Fatimah
core
Models of youth’s family relations in Penza region
Известия высших учебных заведений. Поволжский регион: Общественные наукиBackground. The Russian family is going through a difficult period of its devel-opment, characterized by a number of trends such as the normalization of cohabitation, the postponement of marriage and childbirth, and the popularization of “childfree ...
A.M. Ivanishko
doaj +1 more source
InkanyisoThe erosion of the term ‘Father’ from societal vocabulary reflects a deeper social and spiritual crisis in African communities. This article examines how Christianity and colonialism disrupted African family structures and aims to propose pathways for ...
Sifiso Khuzwayo, Wessel Bentley
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Coherence between values and successor socialization: Facilitating family business continuity [PDF]
The problem of CEO succession is critically important yet unique and distinct from that of turnover at other levels. Research in management agrees with the findings in family business research regarding the preference for an insider as successor, more ...
Garcia Alvarez, Ercilia, Lopez, Jordi
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, 2013 This chapter concerns the intersection of art and power in the Roman world, as well as how we study Roman art. A common emphasis on the formal qualities of so-called Romanized art has created the perception of art as symbolic of the success of Rome and of the acquiescence of indigenous peoples to its rule.
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