Results 91 to 100 of about 10,526,884 (291)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Exploring Community Based Responses and the Natural History of a Drug Market
Social Work and Society, 2015 Previous studies portray open drug market neighborhoods as uniformly poor, urban, socially disorganized, with weak informal social control. Further, open drug market neighborhoods appear sui genesis.
Wes Abercrombie, Mitchell Mackinem
doaj
TRADATIONAL FAMILY VALUES AND CONTEMPORARY CHALLENGES OF AZERBAIJANIS [PDF]
مجلة الاجتهاد للدراسات القانونية والاقتصادية, 2019 Under conditions of globalization traditional moral values in the modern Azerbaijani family are subjected to change. The characteristic of a family's activity, which is a complicated social phenomenon, is determined by a number of different conditions ...
Dr. Nuruzade sahla
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Work Values in Western and Eastern Europe [PDF]
The paper reports on work values in Europe. At the country level we find that job satisfaction is related to lower working hours, higher well-being, and a higher GDP per capita.
Benno Torgler
core
Family history scripts [5 of 5]
, 2022 This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Armytage Family
core
Frontiers in Pharmacology, 2016 Introduction: Health-related quality of life (HRQOL) has become an important measure to identify and shape effective and patient-relevant healthcare interventions innovations through outcomes.
Tanja Kastien-Hilka +9 more
doaj +1 more source
Do family values and reproductive health knowledge influence reproductive health-promoting behaviors in married women? A cross-sectional survey. [PDF]
Korean J Women Health Nurs, 2022 Yun SJ, Kim HY.
europepmc +1 more source