Results 101 to 110 of about 6,976,149 (315)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Racial Ethnic Equality in Child Well-Being from 1985-2004: Gaps Narrowing, but Persist [PDF]
, 2008 Analyzes changes in safety/behavioral concerns, family economic well-being, health, community connectedness, educational attainment, social relationships, and emotional/spiritual well-being by race and ethnicity.
Donald J. Hernandez +1 more
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
The Impact of Complex Family Structure on Child Well‐being: Evidence From Siblings [PDF]
, 2018 Evidence from the United Kingdom Millennium Cohort on children at ages 3 and 5 with older siblings addresses the questions of whether those living with both biological parents and only full siblings have better emotional and behavior outcomes than other ...
Heather, Joshi +2 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Christian Family as Domestic Church in the Writings of St. John Chrysostom [PDF]
, 2013 Translated by Wacław GrzybowskiJohn Chrysostom, the most famous preacher of the Eastern Empire, exerted an important influence on the formation of family.
Widok, Norbert
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The Role of Motivational Persistence and Resilience Over the Well-being Changes Registered in Time [PDF]
, 2015 The present study investigates the interaction between personal characteristics that are considered nowadays strengths used to face difficult events or transition period.
Bostan, Cristina Maria
core
Impact of the Nursing Home Visit to the newborn/ infant/family [PDF]
, 2018 Objective: To identify the impact of the home visit to the newborn/infant/family, when performed by nurses, on the health and well-being of the child and family.
Branca, Vera, Calado, Gabriela
core +1 more source