Results 131 to 140 of about 2,169,555 (268)

Parental Burnout: A Progressive Condition Potentially Compromising Family Well-Being-A Narrative Review. [PDF]

Healthcare (Basel)
Bogdán PM, Varga K, Tóth L, Gróf K, Pakai A.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Culture and Family Well-Being: Exploring Cross-Cultural Similarities and Differences in Family Well-Being

Sri Lanka Journal of Social Work
Wellbeing is multifaceted construct, which encompasses physical, social and mental health. Family can be defined as a group of individuals bound together by marriage, blood or adoption, living together in a single home and interacting with one another in their social roles typically those of spouses, parents, children and siblings.
openaire   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Caregiver burden, social support, and family well-being among caregivers of common mental disorder patients in Bhopal. [PDF]

J Educ Health Promot
Ratre D, Gupta R, Martis M, Singh V.
europepmc   +1 more source

The Association Between Electronic Device Use During Family Time and Family Well-Being: Population-Based Cross-Sectional Study. [PDF]

J Med Internet Res, 2020
Zhao SZ, Guo N, Wang MP, Fong DYT, Lai AYK, Chan SS, Lam TH, Ho DSY.   +7 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

COVID-19 Stress and Family Well-Being: The Role of Sleep in Mental Health Outcomes for Parents and Children. [PDF]

Children (Basel)
Ilie A, Kim AJ, DesRoches D, Keys E, Sherry SB, Stewart SH, Deacon SH, Corkum PV.   +7 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source