Results 171 to 180 of about 9,473,854 (348)

Hubungan Family Well-Being dengan Subjective Well-Being pada Generasi Alpha

open access: yesJurnal Pendidikan Indonesia
Generasi alpha lahir pada era kemajuan teknologi yang sangat pesat membuat generasi ini menjadi sangat terikat pada teknologi dan individualis. Hal ini menyebabkan mereka menjadi terisolasi secara sosial dan berdampak pada rendahnya subjective well-being. Salah satu faktor yang mempengaruhi subjective well-being adalah family well-being. Penelitian ini
Gracalfa Indah Putri Yordan   +3 more
openaire   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Family-friendly work conditions and well-being among Malaysian women

open access: yesWomen's Health
Background: Although participation in paid work improves women’s quality of life and well-being, the health benefits decline for women with young children.
Nadirah Mat Pozian   +2 more
doaj   +1 more source

Strengthening System and Implementation Research Capacity for Child Mental Health and Family Well-being in Sub-Saharan Africa. [PDF]

open access: yesGlob Soc Welf, 2022
Mbwayo A   +11 more
europepmc   +1 more source

Universal Child Care, Maternal Labor Supply, and Family Well‐Being

open access: yesJournal of Political Economy, 2005
Michael Baker   +2 more
semanticscholar   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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