Results 71 to 80 of about 19,342 (292)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Miyazaki Hayao’s Kaze tachinu (The Wind Rises) as an Homage to Hori Tatsuo

open access: yesBunron, 2017
This study analyzes Miyazaki Hayao’s movie Kaze tachinu as an homage to the writer Hori Tatsuo’s famous novel Kaze tachinu, and also takes into account Miyazaki’s earlier comic version of Kaze tachinu (by the same title). While both titles are taken from
Niels Hendrik Bader
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Wartime challenges for trade marks: how long will Russia continue to protect famous foreign marks?

open access: yes, 2023
Since Russia launched a military attack on Ukraine in early 2022, hundreds of foreign companies have left the Russian market, making lawyers wonder what may happen to these entities’ trade marks in the country.
Sevastianova, Vera, Calboli, Irene
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Codification of new tendencies of using non-sexist language in Spanish

open access: yesИбероамериканские тетради, 2018
At the end of 2009 the Royal Spanish Academy published the “New Grammar of the Spanish Language”, the first academic grammar since 1931. It is a collective, pan-hispanic, descriptive, normative, synthetic and practic grammar that combines traditions and ...
Marina Krugova
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The motif of forgiveness in the Russian romantic poetry of the first third of the 19th century

open access: yesСлово.ру: балтийский акцент, 2015
This article considers works of two famous Russian poets of the first third of the 19th century. Both works depict the violation of the sixth commandment - ‘thou shalt not kill’. An axiological analysis of the plot and composition structure of both poems
Zhilina N.
doaj  

Les questions de Diderot sur l’état de la Russie, les réponses de Catherine II et la problématique du despotisme éclairé

open access: yesAstérion
The conversations between Diderot and Catherine II of Russia are often viewed as a dialogue between two persons who embody two contrasting or at least parallel worlds: the philosophy of the Enlightenment and the pragmatism of the Russian autocrat.
Sergueï Karp
doaj   +1 more source

Charles Wiener o el disfraz de una misión lúcida

open access: yesBulletin de l'Institut Français d'Études Andines, 2003
Charles Wiener was one of the most famous explorators of his time for his contribution to the knowledge of prehispanical Peru. Thanks to the collections he brought to France, as well as to his publications.
Pascal Riviale
doaj   +1 more source

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