Results 41 to 50 of about 1,595,600 (284)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Impact of the turbulence modeling approach on the accuracy of the fan noise level prediction

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2018
The fan is the dominant source of noise for modern high bypass ratio aircraft engines. The article presents the results of investigating the influence of the approach to modeling the turbulence in modeling fan stage noise generation on the results of ...
K. R. Pyatunin, N. V. Arkharova
doaj   +1 more source

Numerical Investigation of Unsteady Flow and Aerodynamic Noise Characteristics of an Automotive Axial Cooling Fan

open access: yesApplied Sciences, 2020
Low-speed axial cooling fans are frequently used to manage engine temperature by ensuring that adequate quantities of air pass through heat exchangers, even at low vehicle speeds or in the idle condition. This study aims to provide a better understanding
Jang-oh Mo, Jae-hyuk Choi
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Experimental investigations on the performance and noise characteristics of a forward-curved fan with the stepped tongue

open access: yesMeasurement + Control, 2019
This work presents an experimental study to investigate the influence of step volute tongue on aerodynamic performance and aeroacoustic behavior of a forward-curved fan.
Hui Yang   +7 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Use of fan rig data for the understanding and prediction of fan broadband noise and noise changes due to a variable area nozzle

open access: yes, 2009
This thesis presents the results of the research component of this EngD, entitledUse of fan rig data for the understanding and prediction of fan broadband noise and noisechanges due to a variable area nozzleAs suggested by the title, fan rig noise ...
Deane, Eugene Pio
core   +1 more source

Realizable k-ε Model-Based Gradual-Radius Volute Tongue on Aerodynamic Performance and Noise of Multi-Wing Centrifugal Fan

open access: yesApplied Sciences
The multi-wing centrifugal fan is an important part of air conditioning systems, particularly in the automotive domain. Due to the compact structure and short blade passage of the fan, it may reduce the aerodynamic performance and generate noise.
Yizhe Huang   +5 more
doaj   +1 more source

Research on the Fault Diagnosis Method of Mine Fan Based on Sound Signal Analysis

open access: yesAdvances in Civil Engineering, 2021
The underground local fan and auxiliary fan also play a vital role in the underground air quality, compared with the system fan. However, the number of underground local fans and auxiliary fans is large and widely distributed, which is disadvantageous to
Shijie Song, Dandan Qiu, Sunwei Qin
doaj   +1 more source

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