Results 71 to 80 of about 1,377,910 (300)
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
The Star Wars franchise, fan edits, and Lucasfilm [symposium]
Transformative Works and Cultures, 2012 Fan edits assert that fan authority is on par with that of a work's original creator; this authority is generated not only through the argument, but through the structure of the text itself.
Forrest Phillips
doaj +1 more source
Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel +5 more
wiley +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
The supersonic fan engine: An advanced concept in supersonic cruise propulsion [PDF]
Engine performance and mission studies were carried out for turbofan engines equipped with supersonic through-flow fans. The mission was for a commercial supersonic transport with a Mach 2.32 capability.
Franciscus, L. C.
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
Experimental and analytical dynamic flow characteristics of an axial-flow fan from an air cushion landing system model [PDF]
An investigation was conducted to compare the steady-state and dynamic flow characteristics of an axial-flow fan which had been used previously as the air supply fan for some model air cushion landing system studies.
Boghani, A. B. +2 more
core +1 more source
Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley +1 more source
Creatio Fantastica, 2017 Reviewed book: Michał Cetnarowski, Podwójna tożsamość bogów. O kulturze popularnej w kinie, komiksie i literaturze, Kraków Wydawnictwo SQN 2017, ISBN 978-83-65836-36 ...
Barbara Szymczak-Maciejczyk
doaj +1 more source