Pembrolizumab for Fanconi anemia with advanced tongue cancer
Otolaryngology Case Reports, 2022 Introduction: With underlying Fanconi Anemia, head and neck cancer treatment options are usually limited due to the chromosome instability. Pembrolizumab plays a vital role in head and neck cancer with recurrence and distant metastases.
Keitaro Nagano +3 more
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Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector. [PDF]
, 2010 One of the major hurdles for the development of gene therapy for Fanconi anemia (FA) is the increased sensitivity of FA stem cells to free radical-induced DNA damage during ex vivo culture and manipulation.
Adair, J +10 more
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Current Biology, 2017 Rodríguez and D'Andrea introduce the Fanconi anemia pathway and its role in DNA repair and other cellular functions.
Alfredo, Rodríguez, Alan, D'Andrea
openaire +2 more sources
Case series of Fanconi anemia in Hevi pediatric hospital-Duhok [PDF]
Zanco Journal of Medical Sciences, 2018 Background and objective: Fanconi anemia is a rare inherited autosomal recessive disease characterized by chromosomal instability, progressive bone marrow failure, congenital malformations, and a high propensity of malignancies.
Adnan A.S. Al-Doski
doaj +1 more source
Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023 Pancytopenia is a reduction in all the three peripheral blood cell lineages and presents as anemia, leukopenia, and thrombocytopenia. Aplastic anemia is pancytopenia with bone marrow hypocellularity.
Manaswini Edara +3 more
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Anesthesia for a patient with Fanconi anemia for developmental dislocation of the hip: a case report
Brazilian Journal of Anesthesiology, 2014 Fanconi anemia is a rare autosomal recessive inherited bone marrow failure syndrome with congenital and hematological abnormalities. Literature regarding the anesthetic management in these patients is limited.
Zafer Dogan +4 more
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Acquisition of Relative Interstrand Crosslinker Resistance and PARP Inhibitor Sensitivity in Fanconi Anemia Head and Neck Cancers [PDF]
, 2015 PURPOSE: Fanconi anemia is an inherited disorder associated with a constitutional defect in the Fanconi anemia DNA repair machinery that is essential for resolution of DNA interstrand crosslinks.
Andreassen, Paul R. +11 more
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Oral human papillomavirus is common in individuals with Fanconi anemia [PDF]
, 2015 Fanconi anemia is a rare genetic disorder resulting in a loss of function of the Fanconi anemia-related DNA repair pathway. Individuals with Fanconi anemia are predisposed to some cancers, including oropharyngeal and gynecologic cancers, with known ...
Brown, Darron R. +12 more
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Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patients [PDF]
, 2012 © 2012 Joksic et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium ...
Guc-Scekic, M +11 more
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Immune thrombocytopenia in two unrelated Fanconi anemia patients – a mere coincidence?
Frontiers in Pediatrics, 2015 Thrombocytopenia and pancytopenia, occurring in patients with Fanconi anemia (FA), are interpreted either as progression to bone marrow failure or as developing myelodysplasia.
Anna eKarastaneva +10 more
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