Results 81 to 90 of about 2,289,814 (238)
Genetic risk factor identification for common epilepsies guided by integrative omics data analysis
Epilepsia, EarlyView.Abstract Objective Genetic generalized epilepsies (GGEs) comprise the most common genetically determined epilepsy syndromes, following a complex mode of inheritance. Although many important common and rare genetic factors causing or contributing to these epilepsies have been identified in the past decades, many features of the genetic architecture are ...
Ashwini Mushunuri +9 more
wiley +1 more source
Combined
, 2023 Hongwen Zhang, Fang Wang, Huijie Xiao
openalex +1 more source
The biology of PKM2 in the metabolism and senescence in diabetic kidney disease
Journal of Diabetes Investigation, EarlyView.ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley +1 more source
Wissler-Fanconi syndrome and related diagnoses: a case report
Open Access Rheumatology: Research and Reviews, 2016 Mustafa Q Albustani,1 Robert F Howard2 1Section of Medicine/Pediatrics, The University of Oklahoma College of Medicine, Tulsa, OK, USA; 2Division of Rheumatology, Utica Park Clinic, Tulsa, OK, USA Introduction: Wissler–Fanconi syndrome is a rare ...
Albustani MQ, Howard RF
doaj
Clinical Management Issues, 2014 Adefovir dipivoxil is a nucleotide analog reverse transcriptase inhibitor used to treat adult patients affected by HBeAg-positive and HBeAg-negative chronic hepatitis B and with clinical evidence of lamivudine-resistant hepatitis B virus (HBV).
Orietta Staltari +5 more
doaj +1 more source
Empagliflozin does not prevent progression of Dent's disease type 1 in a mouse model
Experimental Physiology, EarlyView.Abstract Dent's disease is a rare inherited renal disorder characterized by generalized proximal tubule dysfunction with low molecular weight proteinuria, hypercalciuria, and urinary loss of other solutes. The disease is progressive and leads to chronic kidney disease.
Elise de Combiens +6 more
wiley +1 more source
Early Diagnosis of Fanconi-Bickel Syndrome and a Novel Mutation inSLC2A2 Gene
Haseki Tıp Bülteni, 2019 Fanconi-Bickel syndrome is a metabolic disease caused by mutations in SCL2A2 gene. Hepatic and renal glycogen storage, fasting hypoglycemia, and renal tubular dysfunction are characteristics of the disease that is usually diagnosed at 6-10 months of age.
Ezgi Çelikboya +4 more
doaj +1 more source
Journal of Veterinary Medical Science, 2017 Renal Fanconi syndrome has recently been associated with the ingestion of pet jerky treats from China in mostly small breed dogs in North America, Australia and Europe.
A. Yabuki +5 more
semanticscholar +1 more source
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
Drug-induced renal Fanconi syndrome [PDF]
, 2016 A number of therapeutic drugs are toxic to the kidney proximal tubule (PT) and can cause the renal Fanconi syndrome (FS). The most frequently implicated drugs are cisplatin, ifosfamide, tenofovir, sodium valproate and aminoglycoside antibiotics, and the ...
Bass, P., Hall, A.M., Unwin, R.J.
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