Results 121 to 130 of about 36,188 (304)

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

open access: yesAdvanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo   +20 more
wiley   +1 more source

Web Based Semantic Communities – Who, How and Why We Might Want Them in the First Place

open access: yes, 2006
This paper describes an investigation undertaken as part of the FicNet Human-Computer Interaction project into the online amateur fiction community. By working with the community to determine current practices and areas of concern we consider how future ...
Lawrence, K. Faith, schraefel, m. c.
core  

Pragmatism and Meaning: Assessing the Message of Star Trek: The Original Series [PDF]

open access: yes, 2011
The original Star Trek television series purported to depict a future in which such evils as sexism and racism do not exist, and intelligent beings from numerous planets live in a condition of peace and mutual benefit.
Smith, Anne Collins, Smith, Owen M
core   +1 more source

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

open access: yesAdvanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv   +11 more
wiley   +1 more source

Women & Tolkien: Amazons, Valkyries, Feminists, and Slashers [PDF]

open access: yes, 2018
This paper reports on an early pilot project that asks women who self identify as readers or fans of Tolkien\u27s work and/or teachers who have taught Tolkien\u27s work, and/or scholars who have published on Tolkien\u27s work to answer a few open-ended ...
Reid, Robin A., Dr.
core   +1 more source

Pellet Printing for Soft Robotic Devices

open access: yesAdvanced Science, EarlyView.
Fused Granulate Fabrication (FGF) is established here as a reliable method for fabricating soft, airtight robotic devices. Through coordinated optimization of hardware, material selection, and process parameters, this approach enables high‐speed printing of thermoplastic elastomers with silicone‐like softness and modulus.
Yijia Wu   +6 more
wiley   +1 more source

Robust and Tailored 1D/3D Heterojunction for Efficient and Stable Perovskite Solar Cells

open access: yesAdvanced Science, EarlyView.
This study successfully established a robust 1D/3D heterojunction, characterized by a stable 1D phase, favorable lattice matching, strong interface binding, and effective defect passivation. The resulting epitaxial perovskite film demonstrates preferential vertical orientation of (100) facets, thereby facilitating carriers’ transport and stress relief.
Wending Hao   +7 more
wiley   +1 more source

The Tumblarians [PDF]

open access: yes, 2016
This paper examines the tumblarians as an information community and discusses community membership, information behaviours, and complementary models for a situated understanding of this unique personal-professional community.
Hockin, Tamarack
core   +1 more source

PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping

open access: yesAdvanced Science, EarlyView.
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su   +7 more
wiley   +1 more source

Fandom [PDF]

open access: yes, 2021
Eleonora Benecchi, Erika Wang
openaire   +1 more source

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