Results 91 to 100 of about 1,681,847 (276)

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Free-space terabit/s coherent optical links via platicon frequency microcombs

open access: yeseLight
Coherent frequency microcombs, generated in nonlinear high-Q microresonators and driven by a single continuous-wave laser, have enabled several scientific breakthroughs in the past decade, thanks to their high intrinsic phase coherence and individual ...
Wenting Wang   +17 more
doaj   +1 more source

Mastering Complexity toward High‐Performance Multi‐Principal Element Alloy‐Based Films and Coatings: A Review on Microstructural Regulation and Property Optimization

open access: yesAdvanced Science, EarlyView.
This review provides a comprehensive exploration of microstructure regulation strategies for multi‐principal element alloy‐based films and coatings, with a focus on the interplay between elemental composition, nanoscale architecture, heterostructures and interfacial engineering in tailoring their properties and functions. A systematic analysis of their
Jiaming Cao   +4 more
wiley   +1 more source

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

open access: yesAdvanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi   +16 more
wiley   +1 more source

Early prehospital mechanical cardiopulmonary resuscitation use for out-of-hospital cardiac arrest: an observational study

open access: yesBMC Emergency Medicine
Background The use of mechanical cardiopulmonary resuscitation device has been very prevalent in out-of-hospital cardiac arrest rescue. This study aimed to investigate whether the timing of mechanical cardiopulmonary resuscitation device set-up ...
Ying-Kuo Liu   +6 more
doaj   +1 more source

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang   +10 more
wiley   +1 more source

ERESUS CINNABARINUS (OLIVIER, 1789) (ARANEAE, ERESIDAE) ÖRÜMCEĞİNİN ZEHİR AYGITI ÜZERİNE MORFOLOJİK BİR ÇALIŞMA

open access: yesSüleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2009
A MORPHOLOGICAL STUDY ON THE VENOM APPARATUS OF THE SPIDER ERESUS CINNABARINUS (OLIVIER, 1789) (ARANEAE, ERESIDAE) Abstract: In this study, morphological structure of the venom apparatus of Eresus cinnabarinus was studied using scanning electron ...
Kültiğin ÇAVUŞOĞLU
doaj  

Fang Fang [PDF]

open access: yesCurrent Biology, 2011
openaire   +1 more source

Irgm1 Improves Postinfarction Cardiac Repair by Promoting Neutrophil Clearance and Efferocytosis

open access: yesAdvanced Science, EarlyView.
The Irgm1‐PDIA3 axis enhances post‐infarction cardiac repair by accelerating neutrophil clearance and facilitating efferocytosis. Irgm1 holds potential as a prognostic biomarker in MI, and LOC14 may represent a therapeutic option to improve cardiac repair, especially in cases of Irgm1 deficiency.
Zeng Wang   +14 more
wiley   +1 more source

Fonología segmental del Fang ntumu.

open access: yesRevista de Filología Románica, 1991
Sin ...
Álvaro Alonso
doaj  

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