Results 51 to 60 of about 51,874 (288)

Forty years of Fanger’s model of thermal comfort: comfort for all? [PDF]

open access: yesIndoor Air, 2008
The predicted mean vote (PMV) model of thermal comfort, created by Fanger in the late 1960s, is used worldwide to assess thermal comfort. Fanger based his model on college-aged students for use in invariant environmental conditions in air-conditioned buildings in moderate thermal climate zones.
openaire   +2 more sources

TGM2 Aggravates Acute Pancreatitis by Impairing Macrophage Efferocytosis Through Inhibition of the STAT6–GAS6 Axis

open access: yesAdvanced Science, EarlyView.
This study shows TGM2 is upregulated in AP, impairing macrophage efferocytosis by inhibiting the STAT6–GAS6 axis. The lactoferrin‐modified, ROS‐responsive LF‐LNP@si‐TGM2 targets pancreatic macrophages, silences TGM2, restores the axis, and alleviates AP.
Xuxu Liu   +8 more
wiley   +1 more source

Crime and Punishment in Translation: Raskolnikov Redeemed [PDF]

open access: yes, 2014
Until one determined, nearly blind housewife came onto the literary scene, most Westerners had never heard of Dostoevsky without having a personal background in the Russian Language.
Myers, Lindsey C
core   +1 more source

Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation [PDF]

open access: yes, 2019
The aberrant activation of hedgehog (HH) signaling is a leading cause of the development of medulloblastoma, a pediatric tumor of the cerebellum. The FDA‑approved HH inhibitor, Vismodegib, which targets the transmembrane transducer SMO, has shown limited
Agostinelli, Enzo   +20 more
core   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Image1_Yi-Zhi-Fang-Dai Formula Exerts Neuroprotective Effects Against Pyroptosis and Blood–Brain Barrier–Glymphatic Dysfunctions to Prevent Amyloid-Beta Acute Accumulation After Cerebral Ischemia and Reperfusion in Rats.TIF

open access: green, 2021
Zhongkuan Lyu (11838746)   +6 more
openalex   +2 more sources

Cockroach‐Derived Leucokinin VIII Peptide Accelerates Diabetic Skin Wound Healing by Enhancing Keratinocyte Filopodia Formation

open access: yesAdvanced Science, EarlyView.
This study identifies the cockroach‐derived peptide leucokinin VIII as a potent accelerator of diabetic wound healing. By activating the FAK‐ACTG1 axis, the peptide drives keratinocyte migration and filopodia formation. Delivered via a developed PLGA‐PEG‐PLGA thermosensitive hydrogel for sustained release, this approach significantly hastens wound ...
Zhengshan Qin   +11 more
wiley   +1 more source

Supplemental Table S6: from Evolutionary allometry and ecological correlates of fang length evolution in vipers

open access: green, 2022
Matthew L. Holding   +11 more
openalex   +1 more source

Soft Robotics and Advanced Technologies for Minimally Invasive Bioprinting: The Future of Internal Organ Repair

open access: yesAdvanced Science, EarlyView.
This review examines the evolution of bioprinting toward minimally invasive in situ strategies for internal organ regeneration. It defines the technological roadmap from handheld systems to advanced minimally invasive bioprinting platforms, positioning soft robotics as a core enabler.
Duc Tu Vu   +9 more
wiley   +1 more source

Hvad fanger elevers interesse i undersøgende litteraturundervisning?

open access: yesActa Didactica Norden
Elevinteresse er en afgørende forudsætning for undersøgende litteraturundervisning. Hvor instrumentel litteraturanalyse ligesom andre rutineprægede skoleopgaver kan gennemføres, så længe eleverne accepterer de ydre grunde for undervisningen, afhænger undersøgende litteraturundervisning i højere grad af den enkelte elevs personlige grunde eller ...
Tom Steffensen, Thomas Illum Hansen
openaire   +3 more sources

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