Results 61 to 70 of about 20,529 (131)
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis +9 more
wiley +1 more source
A bottom-up approach to find lead compounds in expansive chemical spaces
Drug discovery starts with the identification of a “hit” compound that, following a long and expensive optimization process, evolves into a drug candidate. Bigger screening collections increase the odds of finding more and better hits.
Álvaro Serrano-Morrás +19 more
doaj +1 more source
ABSTRACT Background Cervical cancer (CC) is a main malignancy affecting women globally, with a high mortality rate. Chemoradiotherapy resistance is a significant factor in determining treatment outcomes, and prognostic biomarkers are essential for the appropriate selection of therapeutic strategies.
Angelo Borges de Melo Neto +14 more
wiley +1 more source
A green chiral HPLC method was developed and validated for the determination of lumefantrine enantiomers. The method employs ethanol as a mobile phase as a sustainable and efficient alternative to hexane. The chiral recognition mechanism and elution order of the enantiomers were investigated using electronic circular dichroism and molecular docking ...
Amanda Mohr +4 more
wiley +1 more source
Peer reviewers published in 2014 [PDF]
Editor Jefe Farmacia Hospitalaria
doaj +1 more source
Fasciolosis, caused by Fasciola hepatica, is a parasitic zoonosis that induces liver fibrosis in infected hosts, including ruminants and humans. Extracellular vesicles secreted by F.
Aránzazu González‐Arce +4 more
doaj +1 more source
Lymphatic filariasis (LF) is endemic in Mozambique, where it is caused by Wuchereria bancrofti with Culex quinquefasciatus as the main vector. It affects approximately 10% of the population (2 million) with about 16 million at risk.
Isabel Manhenje +2 more
doaj +1 more source

