Results 81 to 90 of about 191,797 (239)
Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.Heterogeneous‐catalyzed selective and versatile hydrogenative functionalizations of phthalimides have been developed for the first time. By using a solid nanocomposite formed by [Ag/Al2O3] material in combination with [H‐BETA] zeolite as cocatalyst, a broad range of 3‐functionalized isoindolinones have been accesed in one‐pot from phthalimides, H2 and ...
Carles Lluna‐Galán +2 more
wiley +1 more source
Quimiogenómica y Quimiogenética: Definiciones, técnicas y aplicaciones en el ámbito farmacéutico
Tecnología en Marcha, 2020 En los años 80, tomó fuerza la ciencia dirigida al estudio del genoma humano, cuyo objetivo era mejorar la salud humana a través de la identificación de genes.
doaj +1 more source
Biological evaluation and molecular modelling of didanosine derivatives [PDF]
, 2014 Five carbonate derivatives of 50-O-20,30-dideoxyinosine (DDI, 1) have been synthesized by combination with aliphatic alcohols, with their in vitro anti-HIV activity and cytotoxicity being evaluated afterward in human peripheral blood mononuclear cells ...
Briñon, Margarita Cristina +6 more
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ChemElectroChem, Volume 13, Issue 9, 5 May 2026.This study shows that the beneficial effect of Nb by Ti partial substitution on TiO2 consists of a significant increase in the lithium diffusion coefficient, resulting from the opening of structural tunnels. This explains the intercalation pseudocapacitive behavior of Nb‐derivatives of TiO2. The electrochemical performance of a rutile with high niobium
Andrés Solana +2 more
wiley +1 more source
Update on the fluorometric measurement of enzymatic activities for Lysosomal Storage Disorder detection: The example of MPS VI [PDF]
, 2017 Lysosomal Storage Disorders (LSD) are rare diseases that as a whole havea combined incidence ranging from 1:1500 to 1:7000 live births. One of suchdiseases is Mucopolysaccharidosis VI (MPS VI), or Maroteaux Lamy Syndrome.MPS VI patients undergo ...
Adamo, Ana María +5 more
core
Sphingolipids as emerging mediators in retina degeneration [PDF]
, 2019 The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber +3 more
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British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1397-1405, May 2026.Aims Tranexamic acid (TXA) stabilizes clot formation by inhibiting fibrin degradation and improves postoperative outcomes. However, rare adverse events (e.g., thrombosis, seizures) warrant dose–risk evaluation. This study examines how perioperative blood loss and transfusion practices affect TXA concentrations during paediatric scoliosis surgery ...
Paula Alexandra Sá +4 more
wiley +1 more source
2-arachidonoylglycerol metabolism is differently modulated by oligomeric and fibrillar conformations of amyloid beta in synaptic terminals [PDF]
, 2017 Alzheimer´s disease (AD) is the most prevalent disorder of senile dementia mainly characterized by amyloid-beta peptide (Aβ) deposits in the brain. Cannabinoids are relevant to AD as they exert several beneficial effects in many models of this disease ...
Gaveglio, Virginia Lucía +3 more
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Biomedical Chromatography, Volume 40, Issue 5, May 2026.ABSTRACT The Copaifera species are traditionally used for their anti‐inflammatory, antiseptic and healing properties. The objective of this study was to compare the chromatographic profiles of seven samples of copaiba oil‐resin with respect to chromatographic and physicochemical properties and to evaluate their biological activities.
Gabriel de A. P. Graça +13 more
wiley +1 more source