Results 131 to 140 of about 2,791 (152)

Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 1

Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 1
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Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 1

Biochemical and Biophysical Research Communications, 2021
Epithelial ovarian cancer (EOC) is the seventh most common cancer worldwide and the deadliest gynecological malignancy because of its aggressiveness and high recurrence rate. To discover new therapeutic targets for EOC, we combined public EOC microarray datasets with our previous in vivo shRNA screening dataset.
Aya Nakae, Michiko Kodama, Kenjiro Sawada   +2 more
exaly   +3 more sources

Abstract 395: Farnesyl diphosphate farnesyltransferase induces metastasis via upregulating secreted phosphoprotein 1 in non-small cell lung cancer.

Cancer Research, 2013
Abstract Identifying cancer progression associated genes that predicting patient outcome might provide opportunities for developing better therapeutic strategies for lung cancer patients. In the present study, we investigated whether farnesyl diphosphate farnesyltransferase (FDFT1), an enzyme of mevalonate pathway, is a potential ...
Yi-Fang Yang, Yi-Hua Jan, Michael Hsiao
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FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE 1 IS ASSOCIATED WITH THE GROWTH OF RENAL CANCER : ASSOCIATION WITH ANTICANCER EFFECT OF STATIN

Journal of Urology, 2009
Hidekazu Koike, Yoshitaka Sekine, Yasuyuki Morikawa, Yosuke Furuya, Hiroshi Matsui, Kazuhiro Suzuki   +5 more
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1032 FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE 1 IS ASSOCIATED WITH THE GROWTH OF RENAL CANCER: ASSOCIATION WITH ANTICANCER EFFECT OF STATIN

European Urology Supplements, 2009
H. Koike, Y. Sekine, Y. Morikawa, Y. Furuya, M. Matsui, K. Suzuki   +5 more
openaire   +1 more source

ASSOCIATION BETWEEN COMMON SEQUENCE VARIANTS IN THE FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE 1 (FDFT1) GENE AND THE PROSTATE CANCER RISK IN THE JAPANESE POPULATION

Journal of Urology, 2009
Yuji Fukuma, Hiroshi Matsui, Tatsuya Hamano, Nobuaki Ohtake, Seiji Nakata, Kazuhiro Suzuki   +5 more
openaire   +1 more source

A New Class of Highly Potent Farnesyl Diphosphate-Competitive Inhibitors of Farnesyltransferase

Journal of Medicinal Chemistry, 1998
Y Iwasawa
exaly  

A versatile photoactivatable probe designed to label the diphosphate binding site of farnesyl diphosphate utilizing enzymes

Bioorganic and Medicinal Chemistry, 2009
Fernando López-Gallego, Claudia Schmidt-Dannert, David K Shintani   +2 more
exaly  

Analogs of farnesyl diphosphate alter CaaX substrate specificity and reactions rates of protein farnesyltransferase

Bioorganic and Medicinal Chemistry Letters, 2016
Benjamin C Jennings, Yen-Chih Wang, Richard A Gibbs   +2 more
exaly  

An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthases

Analytical Biochemistry, 2012
Jonathan K Dozier, Mark D DiStefano
exaly