Results 61 to 70 of about 2,596 (228)

A Complete Expression Profile of Matrix-Degrading Metalloproteinases in Dupuytren’s Disease [PDF]

open access: yes, 2007
Dupuytren’s disease (DD) is a common fibrotic condition of the palmar fascia, leading to deposition of collagen-rich cords and finger contractions. The metzincin superfamily contains key enzymes in the turnover of collagen and other extracellular matrix ...
Adrian J. Chojnowski   +48 more
core   +1 more source

Negative pressure wound therapy as a definitive treatment for upper extremity wound defects: A systematic review

open access: yesInternational Wound Journal, Volume 16, Issue 4, Page 960-967, August 2019., 2019
Negative pressure wound therapy (NPWT) represents one of the many solutions for complex wounds of the upper extremity. The goal of this study was to investigate the most common indications for definitive treatment of wound defects in the upper extremity with NPWT and to report revision surgery outcomes after its use.
Julien Shine   +5 more
wiley   +1 more source

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): baseline data from day surgery practice in the UK

open access: yesAnaesthesia, EarlyView.
Summary Introduction Most patients undergoing elective surgery in the UK are discharged from hospital on the same day. Despite this, there is a lack of UK patient‐centred outcome measures relating to quality of recovery, pain and analgesic use. The POPPY study was a UK‐wide prospective, observational study measuring short‐ and longer‐term patient ...
Martha Belete   +2177 more
wiley   +1 more source

Management of a chronic radiation necrosis wound with lyopreserved placental membrane containing viable cells

open access: yesClinical Case Reports, Volume 7, Issue 3, Page 456-460, March 2019., 2019
This case report describes management of a chronic radiation wound in a patient with multiple comorbidities using a lyopreserved placental membrane containing viable cells (vLPM). Positive outcomes suggest that vLPM provides a good conservative management option for patients with compromised wound healing due to radiation and comorbidities.
Matthew J. Regulski   +2 more
wiley   +1 more source

A feasibility study investigating the acceptability and design of a multicentre randomised controlled trial of needle fasciotomy versus limited fasciectomy for the treatment of Dupuytren’s contractures of the fingers (HAND-1): study protocol for a randomised controlled trial

open access: yesTrials, 2017
Background Dupuytren’s contractures are fibrous cords under the skin of the palm of the hand. The contractures are painless but cause one or more fingers to curl into the palm, resulting in loss of function.
Eleanor Harrison   +10 more
doaj   +1 more source

Dupuytren’s Contracture: Epidemiological Patterns and Results Following Radical Fasciectomy [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Dupuytren’s disease is a debilitating condition, affecting the palmar fascia of the hand. Patients develop a flexion contracture and have difficulties in activities of daily living.
Swagat Mahapatra   +6 more
doaj   +1 more source

Comparing Complications and Patient Satisfaction Following Injectable Collagenase Versus Limited Fasciectomy for Dupuytren's Disease: A Systematic Review and Meta-Analysis. [PDF]

open access: yesCureus
Dupuytren's disease (DD) is a fibroproliferative disorder that manifests as an abnormal growth of myofibroblasts, causing nodule formation and contractures and affecting digit function. If left untreated, these contractures can lead to a loss of mobility
Alhebshi ZA   +8 more
europepmc   +2 more sources

Collagen organisation in the fibrous joint capsules in the digits of the human hand

open access: yesJournal of Anatomy, EarlyView.
The function of the finger joints is important for daily life. In this review of the literature, we consider the role of collagen and its organization within the fibrous finger joint capsules of the interphalangeal (IP) joints and investigate the relationships between collagen orientation and joint function. Abstract Normal function of the hand and, in
Fiona R. Saunders   +3 more
wiley   +1 more source

Isolated Small Finger Distal Interphalangeal Joint Dupuytren’s Contracture

open access: yesCase Reports in Orthopedics, Volume 2019, Issue 1, 2019., 2019
Dupuytren’s contracture is a disease involving abnormal myofibroblast proliferation and collagen deposition leading to the formation of pathologic cords in the hand. Given that Dupuytren’s contractures rarely extend to the distal interphalangeal joint (DIP), affecting only 5% of patients, there are few cases reported in the literature.
Syed K. Mehdi   +5 more
wiley   +1 more source

Healthcare Costs and Resource Use of Patients with Dupuytren Contracture Treated with Collagenase Clostridium Histolyticum or Fasciectomy: A Propensity Matching Analysis

open access: yesClinicoEconomics and Outcomes Research, 2020
Vladimir Zah,1 Jovana Pelivanovic,1 Simona Tatovic,1 Djurdja Vukicevic,1 Martina Imro,1 Jane Ruby,2 David Hurley2 1Health Economics and Outcomes Research Department, ZRx Outcomes Research Inc., Mississauga, ON, Canada; 2Medical Affairs, Endo ...
Zah V   +6 more
doaj  

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