Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: Expansion of a repertoire of virulence-associated factors [PDF]
Cathepsin L proteases secreted by the helminth pathogen Fasciola hepatica have functions in parasite virulence including tissue invasion and suppression of host immune responses.
Dalton, JP +9 more
core +1 more source
Dysbiosis and Therapeutic Modulation of the Gut Microbiota in Multiple Sclerosis: A Narrative Review
ABSTRACT Background and Aims Multiple sclerosis (MS) is a persistent autoimmune disease that affects the central nervous system. The etiology of MS is complex, involving a variety of genetic and environmental factors. Mounting evidence suggests that dysbiosis significantly impacts the progression of MS mainly through its direct effects upon the immune ...
Mojtaba Memariani, Hamed Memariani
wiley +1 more source
The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis [PDF]
Extracellular vesicles (EVs) released by parasites have important roles in establishing and maintaining infection. Analysis of the soluble and vesicular secretions of adult Fasciola hepatica has established a definitive characterization of the total ...
Bernal, Dolores +11 more
core +1 more source
From cells to pixels: A decision tree for designing bioimage analysis pipelines
Abstract Bioimaging has transformed our understanding of biological processes, yet extracting meaningful information from complex datasets remains a challenge, particularly for biologists without computational expertise. This paper proposes a simple general approach, to help identify which image analysis methods could be relevant for a given image ...
Elnaz Fazeli +4 more
wiley +1 more source
Background: Fascioliasis is a common disease among humans and animals. Having global distribution, disease is developed by hepatic trematodes, Fasciola hepatica and F. gigantica.
KobraKobra PIRI +4 more
doaj
A Consistent PCR-RFLP Assay Based on ITS-2 Ribosomal DNA for Differentiation of Fasciola Species [PDF]
Objective(s): Fascioliasis is a zoonotic parasitic disease caused by liver fluke species of Fasciola hepatica and Fasciola gigantica. Differentiation of these two species, based on their morphological characteristics, is difficult.
Reza Shafiei +2 more
doaj
CIAS detection of Fasciola hepatica/F. gigantica intermediate forms in bovines from Bangladesh [PDF]
Fascioliasis is an important food-borne parasitic zoonosis caused by two trematode species, Fasciola hepatica and Fasciola gigantica. The characterisation and differentiation of Fasciola populations is crucial to control the disease, given the different ...
Ahasan, Syed Ali +9 more
core +1 more source
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior +5 more
wiley +1 more source
A trematode parasite derived growth factor binds and exerts influences on host immune functions via host cytokine receptor complexes [PDF]
The trematode Fasciola hepatica is responsible for chronic zoonotic infection globally. Despite causing a potent T-helper 2 response, it is believed that potent immunomodulation is responsible for rendering this host reactive non-protective host response
A Garcia-Campos +73 more
core +3 more sources
Our study was specifically focused on paramphistomes, with particular attention to their prevalence and associated pathology in the rumen and liver tissues. The elevator pitch of the manuscript to present the maiden study on extra‐ruminal infection sites of the ruminal flukes. ABSTRACT Paramphistomosis, a parasitic disease of ruminants caused by flukes
Hafiz Muhammad Rizwan +10 more
wiley +1 more source

