Results 61 to 70 of about 225,911 (254)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Children’s clothing collections, problems and perspectives
Children's fashion remains a marginal museological subject in the contemporary museographic landscape and in particular in the institutions that should be in charge of this topic: fashion and local history museums.
Aude Le Guennec, Clare Rose
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Drum magazine project: A decolonial shift in teaching fashion theory and history
The Drum Magazine Project is a cross-institutional teaching and research project designed to explore a decolonial approach to teaching fashion theory and history.
Khaya Mchunu, Kiara Gounder
doaj +2 more sources
Les collections de vêtements d’enfant, problèmes et perspectives
Children's fashion remains a marginal museological subject in the contemporary museographic landscape and in particular in the institutions that should be in charge of this topic: fashion and local history museums.
Aude Le Guennec, Clare Rose
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Les éditeurs de French Historical Studies lancent un appel à articles pour un numéro spécial de la revue sur le thème de la mode dans l’histoire française, à paraître en 2020. Il n’y a pas longtemps que l’histoire de la mode a commencé à être considérée comme légitime ou comme digne d’intérêt historique.
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

