Results 31 to 40 of about 3,408,169 (306)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nondestructive quantitative model for predicting the residual tensile strength of silk textile cultural heritage based on machine learning

Fashion and Textiles
Silk is susceptible to deterioration induced by light, heat, and moisture, which leads to reduced structural stability and progressive strength loss. However, because destructive analysis is fundamentally unsuitable for silk textile cultural heritage ...
Seonghee Pak, Byoungho Ellie Jin, Changsang Yun   +2 more
doaj   +1 more source

A study of the improvement of foam material sealing technology for wetsuits

Fashion and Textiles, 2019
The purpose of this study is to propose the most suitable sewing method to produce wetsuits using neoprene fabric. To construct a sewing method sample using neoprene fabric, the samples were prepared using two thicknesses (1.5 t and 3 t) of neoprene ...
Heekyoung Oh, Kyung Wha Oh, Soonjee Park
doaj   +1 more source

Using design for upgrading in the fashion industry [PDF]

Journal of Economic Geography, 2009
The purpose of the article is to analyze upgrading by looking at the design of fashion garments. To that end, I use the theoretical concept of contextual knowledge to understand the problems faced by firms, and their staff, that want to upgrade through design.
openaire   +6 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Effect of substrate fabric characteristics on the peel strength of 3D-printed composite fabrics

Fashion and Textiles
This study aimed to analyze those factors affecting the adhesion between substrate fabrics and 3D printing filaments by evaluating the influence of fabric surface characteristics, fiber composition, yarn type, and the fabric’s structure.
Yoojung Han, Changsang Yun
doaj   +1 more source

Circular Economy and Waste in the Fashion Industry [PDF]

Laws, 2019
The fashion industry has to play an important role in the path towards sustainability and the circular economy. Indeed, the fashion industry is a sector with a high environmental impact; it involves a very long and complicated supply chain, which is associated with large consumption of water and energy, use of chemical substances, water and air ...
openaire   +4 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source