Results 111 to 120 of about 2,200,613 (297)

Conducting Controlled human infection model studies in India is an ethical obligation [PDF]

, 2018
Weighing competing obligations and achieving the “greatest balance” of right over wrong guides an individual, an agency or a country in determining what ought to be done in an ethically challenging situation.
Dholakia, S. Y., Dholakia, Saumil
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Sustainable practices of fabric waste among small-scale garment enterprises in the Kumasi metropolis

Sustinere: Journal of Environment and Sustainability
In recent years, fabric waste has become an important sustainability issue that raises concerns and attracts attention from stakeholders in the fashion industries and the media.
Mohammed Ibrahim, Ebenezer Kofi Howard, Emmanuel Amos, George Kwame Fobiri, Maud Schall, Diana Oppong   +5 more
doaj  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Entanglements of a Dress Named Laverne: Threads of Meaning between Humans and Things (and Things)

Fashion Studies, 2019
This is a narrative about a dress named Laverne and a woman named Elizabeth told through Ian Hodder’s proposition about entanglements. Elizabeth Withey wrote a blog called Frock Around the Clock about her lived experience of wearing the black dress ...
Jessica Kennedy, Megan Strickfaden
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Hyper-Consumerism and Abstract Landscape in Asia

Fashion Studies, 2019
This project examines the politics of abstract desire, hyper-consumerism, and the notion of fantasy in the Asian and Chinese fashion industries. The fascination for logos is often rooted in nostalgia and is an important part of the visual landscape in ...
Marie Geneviève Cyr, Joseph Jagos
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Research on the influencing factors of Chinese agricultural brand competitiveness based on DEMATEL-ISM

Scientific Reports
Agricultural products are pivotal to the national economy, and a comprehensive analysis of brand competitiveness significantly contributes to the support of agricultural structural adjustment and modernization.
Huanchen Tang, Xiaodong Liu, Meiyu Li
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source