Results 81 to 90 of about 13,848,804 (312)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Opulent Servitude: Shoplifting in a Culture of Material Excess and Systemic Racism

Fashion Studies, 2019
Why did the latter part of the nineteenth century witness a sudden growth of white, middle class female shoplifters? Psychology tells us that shoplifting is a mental deficiency manifested in women as “kleptomania” (Abelson 4).
Evangeline Holtz Schramek, Carolyn L. Kane   +1 more
doaj   +1 more source

A Study on the Strategies of the Fashion Industry toward Fast Fashion

The Research Journal of the Costume Culture, 2008
Fast fashion is widely accepted in young generation who are eager to the new fashion trends. With the consumers' rapid adoption of fast fashion, fashion retailers have tried to adopt strategies to reflect current and emerging trends as quickly as possible and effectively in current merchandise assortment, raises important issues with respect to the ...
null 임성민, null 김미숙, null 최주영   +2 more
openaire   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Sine Qua Non: An Exploration of a “Catholic Imagination” at the Met

Fashion Studies, 2019
Recently, the Metropolitan Museum of Art in New York, a hallowed cultural institution, was transformed into an ecclesiastical couture extravaganza through the installation of the Anna Wintour Costume Institute’s latest exhibition, Heavenly Bodies ...
Mark O'Connell
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Effects of global trade integration on skill polarization and wage disparity

Humanities & Social Sciences Communications
This paper examines how the wage gap and skill distribution among workers with different skills respond to trade integration. Using Chinese city-level data for 2010–2020, we find that trade has a negative impact on the wage gap between middle and primary
Shuyun Chen, Fang Luo, Ting Xiao, Liang Ding   +3 more
doaj   +1 more source

Status, Votive Luxury, and Labour: The Female Rapper’s Delight

Fashion Studies, 2019
Rap and luxury fashion form hip hop’s most unshakable couple. However, female rappers appear to have a more difficult time acquiring and manipulating luxury fashion.
Nigel Lezama
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source