Results 61 to 70 of about 7,124,639 (292)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

La mode au musée : Histoire et enjeux de pratiques au féminin

open access: yesCulture & Musées, 2017
This article examines the role of the female curators within the history of French museums, from the late 19th Century to nowadays. Is there a solid link between women and clothing (essentialist conception) or on the contrary, do women find a way to ...
Damien Delille
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

From heritage to digital fashion: a curriculum integration framework for art and design education

open access: yesFrontiers in Communication
IntroductionThe deserts of Saudi Arabia are rich in rock art and cultural heritage sites, with ancient murals in the AlUla region holding significant symbolic meaning.
Nouf Alsuwaida
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Drum magazine project: A decolonial shift in teaching fashion theory and history

open access: yesDiscern
The Drum Magazine Project is a cross-institutional teaching and research project designed to explore a decolonial approach to teaching fashion theory and history.
Khaya Mchunu, Kiara Gounder
doaj   +2 more sources

THE CURRENT UNDERSTANDING OF FASHION ESSENCE

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2015
The article considers a fashion as a real and an acting social fact that affects many aspects of the life of the individual and society. The interest in the ability to reflect the specific modes of social transformations becomes the basis for ...
Anastasya Aleksandrovna Zhilina   +1 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

About Tools for Management of Fashion and Fashion Communication

open access: yesRUDN Journal of Psychology and Pedagogics, 2018
The problem of fashion as a social phenomenon was studied by the classics of philosophy, sociology, economic theory, starting from the XVIII century. In modern science, fashion is considered as an interdisciplinary phenomenon in the context of culture ...
Andrey A Odintsov, Olga V Odintsova
doaj   +1 more source

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