Results 181 to 190 of about 1,902,938 (304)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

SAKCL: a deep neural network test data selection method based on self-attention and K-means clustering. [PDF]

Sci Rep
Huo T, Sun Q, Ding R.
europepmc   +1 more source

2010 FIT Fashion Show part 2: Intimate Apparel

Intimate Apparel designed by graduating students in FIT's BFA fashion design program.

core  

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Automating the creation of fashion patterns using deep learning algorithms. [PDF]

Front Artif Intell
Alsabhi R.
europepmc   +1 more source

Fashion in the Nineties Symposium: Patricia Mears, "Spectacle: Fashion on Parade"

MFIT Deputy Director Patricia Mears reviews the many groundbreaking runway shows from the 1990s for The Museum at FIT's 26th academic symposium “Reinvention and Restlessness: Fashion in the Nineties” on February 11, 2022.

core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Cultural evolution of beauty standards. [PDF]

Proc Natl Acad Sci U S A
Boucherie L, Kumar S, Ledebur K, Lohse A, Śliwa K.   +4 more
europepmc   +1 more source

2010 FIT Fashion Show part 3: Knitwear, Sportswear, Menswear

Knitwear, Sportswear, and Menswear designed by graduating students in FIT's BFA fashion design program.

core