Results 231 to 240 of about 2,173,989 (307)

Clinical and Nonclinical Determinants of Simultaneous vs Staged Bilateral Total Knee Arthroplasty. [PDF]

Arthroplast Today
Maloy GC, Day W, Halperin SJ, Islam W, Grauer JN, Molloy IB.   +5 more
europepmc   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Broad-scale evaluations of biodiversity change need reference comparisons. [PDF]

Sci Adv
Sinclair JS, Cortés-Guzmán D, Aroviita J, Baker NJ, Barešová L, Bradley C, Cañedo-Argüelles M, Cunillera-Montcusí D, Feeley HB, Ferréol M, Floury M, Forio MAE, Goethals P, González-Ferreras AM, Huttunen KL, Karaouzas I, Larrañaga A, Moe SJ, Moulinec A, Osadčaja D, Pařil P, Peredo Arce A, Polášek M, Straka M, Vannevel R, Wilkes M, Haase P.   +26 more
europepmc   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Strategies and approaches to vector control effectiveness toward the elimination of malaria in mainland Tanzania: An implementation case study analysis. [PDF]

PLOS Glob Public Health
Gitanya MP, Worges M, Koenker H, Kiware S, Lazaro S, Kitau J, Kisinza W, Serbantez N, Kamala B, Dismas C, Matowo J.   +10 more
europepmc   +1 more source

A nationwide student survey on biochemistry learning resources in Italy

FEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti, Ivano Eberini, Maria Luisa Genova, Francesca Mensitieri, Francesco Malatesta   +4 more
wiley   +1 more source

Understanding visual impairment trends in the Gulf Council Countries: An analysis from 1990 to 2021 and time-series predictions for 2030. [PDF]

PLoS One
Al Zomia AS, T Alshahrani S, Ali Al Zehefa I, Jallwi Korkoman A, Abdullah Alamoud A, Abdullah Alqahtani M, Tarek Mirdad M, Tarek Mirdad M, Ahmed A Alnami R, Nasser M Alahmari F, Ali Alshahrani S, Abdulrahman Alyali S.   +11 more
europepmc   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Temporal Trends in Transcatheter Tricuspid Valve Interventions After FDA Approval in the United States. [PDF]

JACC Adv
Rawlley B, Reisinger M, Murphy HR, Harris AH, Barrett T, Wahlberg KJ, Kolte DS, Villablanca P, Lahoud RN, Dauerman HL, Gupta T.   +10 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source