Results 31 to 40 of about 27,721 (266)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Research on the fast charging of VRLA

TELKOMNIKA Indonesian Journal of Electrical Engineering, 2012
VRLA can be the energy storing device of the HEV (Hybrid Electric Vehicle), photovoltaic system and so on. The most important factor that restricts the improvement of these fields is the service lifetime of the battery cannot reach the expectation. In the charging process, traditional charging method has serious polarization phenomenon.
Wu Tiezhou, Cao Quan, Liu Lunan, Xiao Qing, Wang Xieyang   +4 more
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Expanding the Fast Charging Network [PDF]

World Electric Vehicle Journal, 2016
Oregon has more DC Fast Chargers (DCFC) for electric vehicles per capita than any other US region. This network has played a major role in making Oregon one of the strongest markets for electric vehicle sales in the US, despite the lack of a state purchase incentive.
openaire   +1 more source

A Model for Public Fast Charging Infrastructure Needs [PDF]

World Electric Vehicle Journal, 2016
Plug-in electric vehicles can reduce GHG emissions although the low availability of public charging infra-structure combined with short driving ranges prevents potential users from adoption. The rollout and opera-tion, especially of public fast charging infrastructure, is very costly.
Gnann, Till, Goldbach, Daniel, Jakobsson, Niklas, Plötz, Patrick, Bennehag, Anders, Sprei, Frances   +5 more
openaire   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Tailoring ultra-fast charge transfer in MoS ₂

Physical Chemistry Chemical Physics, 2020
Charge transfer dynamics are of importance in functional materials used in devices. This property is morphology dependent in MoS 2 . Compared to a single crystal it is faster in a nanoparticle sample and even faster for a MoS 2 graphene oxide composite.
Fredrik O. L. Johansson, Ute B. Cappel, Mattis Fondell, Yuanyuan Han, Mihaela Gorgoi, Klaus Leifer, Andreas Lindblad   +6 more
openaire   +5 more sources