Results 131 to 140 of about 140,213 (303)
De gemeente Almere wil richting een circulaire economie bewegen, waarin zo min mogelijk grondstoffen gebruikt worden en waarin zo min mogelijk afval ontstaat. Een van de reststromen die een grote milieu-impact hebben is textiel. De indruk bestaat dat steeds meer textiel kortstondig gebruikt wordt of van een zodanige kwaliteit is dat het een korte ...
Faddegon, Krispijn +4 more
openaire +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Printtimalliston suunnitteluprosessi fast fashion -yritykselle [PDF]
Opinnäytetyöni käsittelee suunnitteluprosessia fast fashion -yrityksessä. Oman prosessini kautta selvitän, millaisia vaikutuksia fast fashion -ilmiöllä on tekstiilisuunnittelijan työhön ja, mitä suunnittelijalta vaaditaan nopeatempoisessa ...
Heikkilä, Inna
core
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Fast fashion v podmínkách trvale udržitelného rozvoje
Ježková, M. Fast fashion in conditions of sustainable development. Diploma thesis. Brno: Mendel University, 2020. Diploma thesis focuses on companies which do business in fast fashion while they focus on sustainable development.
Ježková, Markéta
core
Fast Fashion: from accelerating climate change to sustainable fashion
El propósito del estudio estuvo en analizar el impacto del fast fashion en el cambio climático, para comprender las prácticas y dinámicas de la industria de la moda rápida.
Camaño, Jennifer +4 more
core +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source

