Results 131 to 140 of about 140,213 (303)

Fast Fashion in Almere

open access: yes, 2020
De gemeente Almere wil richting een circulaire economie bewegen, waarin zo min mogelijk grondstoffen gebruikt worden en waarin zo min mogelijk afval ontstaat. Een van de reststromen die een grote milieu-impact hebben is textiel. De indruk bestaat dat steeds meer textiel kortstondig gebruikt wordt of van een zodanige kwaliteit is dat het een korte ...
Faddegon, Krispijn   +4 more
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Printtimalliston suunnitteluprosessi fast fashion -yritykselle [PDF]

open access: yes, 2016
Opinnäytetyöni käsittelee suunnitteluprosessia fast fashion -yrityksessä. Oman prosessini kautta selvitän, millaisia vaikutuksia fast fashion -ilmiöllä on tekstiilisuunnittelijan työhön ja, mitä suunnittelijalta vaaditaan nopeatempoisessa ...
Heikkilä, Inna
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Fast fashion v podmínkách trvale udržitelného rozvoje

open access: yes, 2020
Ježková, M. Fast fashion in conditions of sustainable development. Diploma thesis. Brno: Mendel University, 2020. Diploma thesis focuses on companies which do business in fast fashion while they focus on sustainable development.
Ježková, Markéta
core  

Fast Fashion: from accelerating climate change to sustainable fashion

open access: yes
El propósito del estudio estuvo en analizar el impacto del fast fashion en el cambio climático, para comprender las prácticas y dinámicas de la industria de la moda rápida.
Camaño, Jennifer   +4 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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