Results 81 to 90 of about 1,940,502 (297)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Assessment of key sustainability indicators in a UK fast food supply chain: a life cycle perspective [PDF]

open access: yes, 2012
The purpose of this article is to investigate the understanding of businesses and end consumers of key sustainability measures in the UK fast food Supply Chain.
Nabhani, Farhad   +2 more
core  

Prevalence and Associated Factors with Sugar-sweetened Beverages Consumption among Kurdish High-school Children

open access: yesIndian Journal of Community Medicine
Adolescents’ excessive consumption of sugar-sweetened beverages (SSBs) has become a global concern due to its detrimental effects on health. We explored the prevalence and associated factors of the consumption of SSB in high-school children in the ...
Deldar Morad Abdulah   +2 more
doaj   +1 more source

Associations between dietary patterns and metabolic syndrome in adolescents

open access: yesSalud Pública de México, 2019
Objective. Evaluate association of dietary patterns with metabolic syndrome (MetS) and metabolic markers. Mate­rials and methods. 654 adolescents from Guadalajara, Jalisco, participated in a cross-sectional study.
Guadalupe Ramírez-López   +2 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Exposure to Food Advertising On Television: Associations With Children’s Fast Food and Soft Drink Consumption and Obesity [PDF]

open access: yes
There is insufficient research on the direct effects of food advertising on children's diet and diet-related health, particularly in non-experimental settings.
Jennifer L. Harris   +2 more
core  

Culinary competency as a protective factor against ultra-processed food consumption and unhealthy cooking practices: a comparative study between type 1 diabetes patients and healthy controls

open access: yesFrontiers in Nutrition
BackgroundThe rise of ultra-processed foods (UPFs) poses a significant challenge for chronic disease management. Culinary competence (CC) has been described as a behavioral characteristic associated with higher quality dietary patterns.
Adrián Idoate-Bayón   +12 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Effective Factors related to Fast-foods Consumption in Bandar Abbas: A Community-Based Study [PDF]

open access: yes
Background and objective: In recent decades there has been a growing increase in the consumption of fast-foods. As a result of over-consumption of these high-calorie and fatty foods and the unbalance between the received and consumed energy, the chance ...
صفری, علی   +6 more
core  

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