Results 41 to 50 of about 141 (133)

Production of recombinant human granulocyte‐macrophage colony‐stimulating factor in thermoinducible E. coli: Tuning inclusion body architecture and protein yield via dissolved oxygen control

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Recombinant protein expression in Escherichia coli frequently results in the formation of inclusion bodies (IBs), which provide high protein accumulation but often require additional steps to recover functional protein. Although culture conditions strongly influence IB physicochemical and structural characteristics, the impact of ...
Ximena Gómez‐Gil, Norma A Valdez‐Cruz, Sara Restrepo‐Pineda, Nuria Sánchez‐Puig, Rafael Vázquez‐Duhalt, Rubén D Cadena‐Nava, Néstor O Pérez, Mauricio A Trujillo‐Roldán   +7 more
wiley   +1 more source

MOLM: Alleviating Congestion through Multi-Objective Simulated Annealing-Based Load Balancing Routing in LEO Satellite Networks

Future Internet
In satellite networks, existing congestion resolution methods do not consider the predictability and stability of paths, leading to frequent path switches and high maintenance costs.
Yihu Zhou, Haiming Chen, Zhibin Dou
doaj   +1 more source

Integrating Grain to Ground Motion Data for Critical Rock Bridge and Slope Failure Analysis

International Journal for Numerical and Analytical Methods in Geomechanics, EarlyView.
ABSTRACT Rock masses can fail catastrophically with little warning, yet their stability depends on hidden internal connections that channel forces and localise damage. Among these, rock bridges–a “known unknown” in slope mechanics–lock fractured rock and control how failure unfolds, but their concealed geometry and uncertain strength obscure where and ...
Antoinette Tordesillas, Shuo Zhou, Leonnardo Probst, Pat Bellett, Michal Nitka, Jacek Tejchman   +5 more
wiley   +1 more source

Local Fast Segment Rerouting on Hypercubes.

, 2018
Fast rerouting is an essential mechanism in any dependable communication network, allowing to quickly, i.e., locally, recover from network failures, without invoking the control plane. However, while locality ensures a fast reaction, the absence of global information also renders the design of highly resilient fast rerouting algorithms more challenging.
Klaus-Tycho Foerster, Mahmoud Parham, Stefan Schmid 0001, Tao Wen   +3 more
openaire   +4 more sources

Endoscopic small bowel therapies for type 2 diabetes

Nutrition in Clinical Practice, EarlyView.
Abstract Type 2 diabetes is a global epidemic despite current medical treatments. Many patients are not responsive to medications, and patients with obesity are hesitant about bariatric surgery. Studies investigating the metabolic effects of Roux‐en‐Y gastric bypass have increasingly demonstrated that the duodenum plays a key role in the ...
Roma Patel, Zehra Naseem, Prisha Gattu, Stephen Firkins, Roberto Simons‐Linares   +4 more
wiley   +1 more source

Modeled Subsidence of Permafrost Terrain 2025–2050: North‐Central Alaska

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT A large fraction of the Alaska terrain is underlain by regolith that contains excess ice (ice that in volume exceeds the natural pore space). Possible loss of excess ice would lead to ground subsidence, which in turn would disturb and destabilize the ground surface.
Jaakko Putkonen, Hayden Patterson, Robert Chance, Mary Soaper, Anai Caparó Bellido, Aymane Ahajjam, Andrew Wilcox, Sheridan Parker, Timothy Pasch   +8 more
wiley   +1 more source

From Resilience to “Susilience”: Toward Further Theoretical Perspectives in Sustainable Supply Chains

Sustainable Development, EarlyView.
ABSTRACT The increasing exposure of global supply chains to environmental, social, and operational disruptions has intensified scholarly interest in sustainability and resilience. While these concepts are widely discussed, existing research often addresses them separately, preventing understanding of their combined role in supply chain management.
Mahmut Mollaoglu, Bükra Doganer
wiley   +1 more source

Mechanochemically Programmed, Oligomer‐Selective Amyloid Assembly via Axial Rotation

Small, EarlyView.
Tunable axial rotation mechanically redirects amyloid assembly without chemical additives. Low rotational speeds favor fibril maturation, whereas high‐speed rotation suppresses productive fibril amplification and biases the pathway toward oligomer‐enriched assemblies.
Seokbeom Roh, Eunji Song, Minwoo Bae, Da Yeon Cheong, Sechan Han, Taeha Lee, Dain Kang, Jae Eon Lee, Seung Pil Pack, Hyungbeen Lee, Insu Park, Gyudo Lee   +11 more
wiley   +1 more source

A Semi‐Quantitative Methodology for Chemical Process Resilience Assessment

Safety Science and Technology, EarlyView.
A new semi‐quantitative framework is proposed for process resilience assessment. Safety/security, productivity, and quality are integrated into the resilience evaluation. Dynamic simulations are used to quantify resilience as a time‐dependent system response.
Tommaso Capomagi, Ming Yang, Valerio Cozzani   +2 more
wiley   +1 more source

Rerouting reductant flux via protein tethering enhances biohydrogen production in Thermococcus kodakarensis

Applied Microbiology and Biotechnology
Microbes that generate copious amounts of hydrogen (H2) via dark fermentation are a promising means to evolve and improve renewable biofuels. Many anaerobic hyperthermophilic archaea, such as the fast-growing, genetically tractable, heterotroph ...
Sere A. Williams, David A. Crosby, Danielle M. Riley, Teagan P. Rockwood, Brett W. Burkhart, Meghan E. Stettler, Thomas J. Santangelo   +6 more
doaj   +1 more source