Results 51 to 60 of about 160,242 (257)

Transient energy storage systems for fast frequency response: Power‐train considerations

IET Renewable Power Generation
Renewable energy sources generate power intermittently, which poses challenges in meeting power demand. The use of transient energy storage systems (TESSs) has proven to be an effective solution to this issue.
Yiheng Hu, Nigel Schofield, Nan Zhao
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Design of a thermoelectric generator with fast transient response [PDF]

Renewable Energy, 2015
Thermoelectric modules are currently used both in Peltier cooling and in Seebeck mode for electricity generation. The developments experienced in both cases depend essentially on two factors: the thermoelectric properties of the materials that form these elements (mainly semiconductors), and the external structure of the semiconductors ...
Fisac, Miguel, Villasevil Marco, Francisco Javier, López Martínez, Antonio Miguel   +2 more
openaire   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Leveraging Hybrid Filter for Improving Quasi-Type-1 Phase Locked Loop Targeting Fast Transient Response

Energies, 2018
In renewable energy generation applications, phase locked loop (PLL) is one of the most popular grid synchronization technique. The main objective of PLL is to rapidly and precisely extract phase and frequency especially when the grid voltage is under ...
Yunlu Li, Junyou Yang, Haixin Wang, Weichun Ge, Yiming Ma   +4 more
doaj   +1 more source

Transient impairment of the adaptive response to fasting in FXR‐deficient mice [PDF]

FEBS Letters, 2005
The farnesoid X receptor (FXR) has been suggested to play a role in gluconeogenesis. To determine whether FXR modulates the response to fasting in vivo, FXR‐deficient (FXR−/−) and wild‐type mice were submitted to fasting for 48 h. Our results demonstrate that FXR modulates the kinetics of alterations of glucose homeostasis during fasting, with FXR ...
Cariou, Bertrand, Van Harmelen, Kirsten, Duran-Sandoval, Daniel, Van Dijk, Theo, Grefhorst, Aldo, Bouchaert, Emmanuel, Fruchart, Jean Charles, Gonzalez, Frank J., Kuipers, Folkert, Staels, Bart   +9 more
openaire   +4 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source