Results 31 to 40 of about 21,407 (261)
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The voltage stability is an essential security concern when a system is operating in peak load hours or subjected to an N-1 contingency. Among various voltage stability indices, Local Thevenin Index (LTI) has been a popular one, but mostly applied to the
Qingxin Shi +6 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Security constrained reactive power dispatch in electrical power systems [PDF]
With the increased loading and exploitation of the power transmission system and also due to improved optimised operation, the problem of voltage stability and voltage collapse attracts more and more attention .
Chebbo, Ahmad Mustapha
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Analysis on Voltage Stability Indices [PDF]
This thesis discusses the performance of different line voltage stability indices previously studied in literature including Lmn Index, Fast Voltage Stability Index (FVSI), Voltage Collapse Point Indicators (VCPI), and LQP Index, as well as the ...
Doig Cardet, Christine Elizabeth
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Assessment of Voltage Stability Using Network Equivalent
In this paper a fast system voltage stability index (FSVSI) has been proposed to assess overall system voltage stability of a multi-bus power system at a particular operating point using the concept of two bus network equivalent.
Chakrabarti, Abhijit; Bengal Engineering and Science University +3 more
core +1 more source

