Results 111 to 120 of about 8,890 (312)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
IET Radar, Sonar & NavigationA novel method is proposed for rail fastener detection based on millimetre‐wave (mmWave) radar, mmWave radar fastener counter (MMW‐FC), which can accurately detect and record the fasteners in real‐time as the train traverses its route.
Yangang Sun +5 more
doaj +1 more source
FIQ: A Fastener Inspection and Quantization Method Based on Mask FRCN
Applied SciencesRail-fastening components are essential for ensuring the safety of urban rail systems by securing rails to sleepers. Traditional inspection methods rely heavily on manual labor and are inefficient.
Zhanhao Shang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
, 1994 A fastener system is provided for securing a component to supporting structure. The fastener system comprises a pair of cooperating fastener modules. The first module includes a first stationary member attached to the supporting structure and a first ...
Driscoll, Timothy D.
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source