Results 161 to 170 of about 8,890 (312)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Study on the mechanical behavior of ballastless track continuous welded rail on multi-span simply supported steel truss bridge for mixed passenger and freight railway. [PDF]

Sci Rep
Xu H, Xie K, Chen J, Liu W, Lin H.
europepmc   +1 more source

Window Glass Fastener

, 1909
Patent for window glass fastener.
Phinny, Christphee W.
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Spontaneous Aryl Diazonium Treatment of Exposed Carbon Fiber Surfaces for Reducing Galvanic Corrosion at Composite-Aluminum Alloy Joints during Cyclic Accelerated Degradation Testing. [PDF]

ACS Omega
Dammulla IN, Swain GM.
europepmc   +1 more source

String Fastener.

, 1916
Patent for string fastener of a simple construction to fasten a string after it has been arranged around a box, including ...
Hine, Frank B.
core  

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Structural basis for the contribution of latent TGFβ binding protein to TGFβ latency and activation. [PDF]

Nat Commun
Biggin GR, Snee M, Xiao YB, Smedley C, Godwin ARF, Dajani R, Birchenough HL, A Jowitt T, Travis MA, Roseman AM, Tarakanova A, Baldock C.   +11 more
europepmc   +1 more source

Hat fastener

Patent for a fastener that uses combs connected inside the crown of a hat to secure it upon the ...
Mueller, Lisette
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source