Cardiometabolic Risk Profiles Associated with Chronic Gastrointestinal Symptoms in Adults: A Cross-Sectional Exploratory Analysis Using Routine Clinical Markers. [PDF]
Tomuța RA +6 more
europepmc +1 more source
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen +14 more
wiley +1 more source
Intermittent Fasting and Emotional Regulation: A Psychobiological Framework Integrating Metabolic, Neuroendocrine and Interoceptive Mechanisms. [PDF]
D'Aleo E +7 more
europepmc +1 more source
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen +12 more
wiley +1 more source
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang +7 more
wiley +1 more source
Lipid lowering in coronary artery disease - not just statins. [PDF]
Han J, Masmanian E, Wang T, Chua TP.
europepmc +1 more source
Comparison of Fasting and Non Fasting Lipid Profile and Lipoprotein (a) in Healthy Adult Population
openaire +1 more source
Deconstruction of Human Age‐Related Cataract Capsules Defines Aging
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang +9 more
wiley +1 more source
Beneficial Outcome Pathways: A New Mechanistic Framework to Map the Health Effects of Fasting in Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]
Mesnage R, Buchinger V.
europepmc +1 more source
Association of apolipoprotein A1 (rs 5069) genotyping with 25-hydroxyvitamin D deficiency and insulin resistance as a metabolic and genetic difference in obesity and type 2 diabetes mellitus. [PDF]
Usama N +5 more
europepmc +1 more source

