Results 61 to 70 of about 101,312 (250)

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Community data of adults fasting for lipid and diabetes tests in Calgary, Alberta from 2010 to 2016

Data in Brief, 2019
Data presented in this data article include the proportion and counts of community-based adult men and women who fasted for various lipid and diabetes screening-related tests from January 2010 to June 2016 in Calgary, Alberta, Canada.
Irene Ma, Jeannine Viczko, Christopher Naugler   +2 more
doaj   +1 more source

Clinical significance of fasting and postprandial lipemia in obese and non-obese subjects [PDF]

Zanco Journal of Medical Sciences, 2018
Background and objective: Postprandial lipemia is a risk marker for the presence or progression of cardiovascular disease. Identifying factors affecting lipoprotein metabolism in postprandial state is of interest in order to find ways for prevention of ...
Muzha M. Baqi, Abdulqader A. Alnaqishbandi   +1 more
doaj   +1 more source

Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery

Advanced Functional Materials, EarlyView.
This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar, Deeksha Kumaresh, Eduardo Nombera Bueno, Mae Pryor, Paula T. Hammond   +4 more
wiley   +1 more source

Comparison of lipid, liver, and renal parameters between fasting and non-fasting states in apparently healthy adults

Türk Biyokimya Dergisi
Despite the wide acceptability of laboratory assessments during the fasting state in clinical practice, emerging evidence suggests that non-fasting testing offers a convenient alternative, especially for the estimation of lipid profile. The present study
Wasana Keddagoda Gamage Piyumi, De Silva Nayomi Deshani, Attanayake Anoja Priyadarshani, Weerarathna Thilak Priyantha, Wadasinghe Ransika Ransarani   +4 more
doaj   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

Advanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang, Myungji Kim, Hwanyong Choi, Jinseon Park, Minji Kim, Donghwan Kim, Bo Ram Lee, Jinah Jang   +7 more
wiley   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

The effect of Ramadan fasting on lipid profile in pregnant women

Journal of Fasting and Health, 2015
Introduction: Abnormal lipid profile causes maternal mortality and impairs fetal development. This study investigated the effect of Ramadan fasting on plasma lipid profile in pregnant women. Material and Methods: This self-control, cohort study was performed in healthy volunteer fasted pregnant women.
Khoshdel, Abolfazl, Kheiri, Soleiman, Nasiri, Jafar, Saedi, Ebrahim, Mobasheri, Mahmoud   +4 more
openaire   +3 more sources

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Use of Silymarine as Adjuvant in Type 1 Diabetes Mellitus Patients Poorly Controlled with Insulin

مجلة كلية الطب, 2010
Background: Glycemic control and prevention of secondary complications are the most important aims of using pharmacological treatments in diabetes mellitus.
Ahmad T. Numan, Naseer A. Hadi, Nasreen Sh. Mohammed, Saad A. Hussain   +3 more
doaj   +1 more source