Results 101 to 110 of about 21,767 (293)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Supernova Fallback onto Magnetars and Propeller-powered Supernovae [PDF]

open access: yes, 2011
We explore fallback accretion onto newly born magnetars during the supernova of massive stars. Strong magnetic fields (~10^(15) G) and short spin periods (~1-10 ms) have an important influence on how the magnetar interacts with the infalling material. At
Ott, Christian D., Piro, Anthony L.
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Eco-friendly dyeing of leather and wood samples using Parthenocissus quinquefolia L. fruits aqueous extract

open access: yesJournal of New Results in Science
The present study is relevant to extracting natural colorant from Parthenocissus quinquefolia L. fresh fruits and applying the extracted dye on leather and wood samples in the presence and absence of various mordants.
Sedanur Gökçe, Adem Önal
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

VARIABILITY OF FASTNESS PROPERTIES OF URETERS OF ADULT PEOPLE [PDF]

open access: yesСаратовский научно-медицинский журнал, 2007
Investigated fastness properties of ureters of adult people in view of a floor, age and topography-anatomic features. Statistically significant decrease of their fastness with the years is revealed, are noted sexual and bilateral features.
V.N. Nikolenko   +2 more
doaj  

Thin Disk Models of Anomalous X-ray Pulsars

open access: yes, 2003
We discuss the options of the fall-back disk model of Anomalous X-Ray Pulsars (AXPs). We argue that the power-law index of the mass inflow rate during the propeller stage can be lower than those employed in earlier models. We take into account the effect
Alpar   +39 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

COLOUR FASTNESS ANALYSIS OF PRINTED ELECTRONICS THROUGH THE FLEXOGRAPHY TECHNIQUE ON TEXTILE SUBSTRATES [PDF]

open access: yesAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2020
The work is framed within Printed Electronics, an emerging technology for the manufacture of flexible electronic products such as electronic textiles.
RODES-CARBONELL Ana   +3 more
doaj  

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