Results 201 to 210 of about 9,110 (299)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Enhanced Activity of Leather Materials Coated with Silver, Copper and Graphene Oxides-Decorated TiO₂ Nanocomposites and Gamma Irradiated. [PDF]

Materials (Basel)
Gaidau C, Alexe C, Constantinescu RR, Dinca L, Stanculescu I, Cutrubinis M, Cosma D.   +6 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

The Shift to Bio-Based Auxiliaries in Textile Wet Processing: Recent Advances and Industrial Potential. [PDF]

Molecules
Catarino ML, Sampaio F, Pacheco L, Gonçalves AL.   +3 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Artificial neural network-guided phyto-synthesis of Pd/Pt bimetallic nanoparticles on cotton: sustainable textile functionalization with antibacterial and colorimetric properties from saffron waste. [PDF]

Sci Rep
Sadeghi-Kiakhani M, Hashemi E, Norouzi MM, Ramezani AH.   +3 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Evaluating Sustainable Alternatives to Conventional Reduction Clearing in Polyester Dyeing. [PDF]

ACS Omega
Sarwar Z, Siddique A, Rauf F, Chan CK, Saeed A, Liu S, Abid S, Xu Z, Nishonov A.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Synthesis and characterization of novel quinazolinone-based azo disperse dyes: molecular docking, ADMET, <i>in vitro</i>, and dyeing performance on polyester fabric. [PDF]

RSC Adv
Noser AA, Almehizia AA, Al-Omar MA, Alrayes FI, Kareem MM, Alomari KB, Aljowni MA, Ibrahim SA.   +7 more
europepmc   +1 more source