Results 251 to 260 of about 533,332 (304)

Amplification of Endoplasmic Reticulum Stress via Inhibiting Lipid Droplet Formation to Enhance Chemodynamic Immunotherapy

Advanced Science, EarlyView.
An endoplasmic reticulum (ER)‐targeted chemodynamic nanoagent (TCBQ/iLD‐ER NPs) comprising •OH‐generating tetrachloro‐1,4‐benzoquinone (TCBQ) and lipid droplets (LDs) formation inhibitor (iLD) is developed for chemodynamic immunotherapy of tumors. After ingestion by cancer cells, TCBQ/iLD‐ER NPs preferentially accumulate in the ER and react with ER ...
Huilan Cai, Shaoru Zhuang, Yang Zhu, Rujiang Ao, Meili Yu, Tingting Cui, Jun Wang, Xuegang Niu, Hongwei Huang, Shanshan Peng, Yu He, Lisen Lin, Huanghao Yang   +12 more
wiley   +1 more source

New role of fat-free mass in cancer risk linked with genetic predisposition. [PDF]

Sci Rep
Harris BHL, Di Giovannantonio M, Zhang P, Harris DA, Lord SR, Allen NE, Maughan TS, Bryant RJ, Harris AL, Bond GL, Buffa FM.   +10 more
europepmc   +1 more source

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Bioimpedance analysis of fat free mass and its subcomponents and relative associations with maximal oxygen consumption in facioscapulohumeral dystrophy. [PDF]

Eur J Appl Physiol
Crisafulli O, Bottoni G, Lacetera J, Fassio F, Grattarola L, Lavaselli E, Giovanetti G, Tupler R, Negro M, D'Antona G.   +9 more
europepmc   +1 more source

Varying optimal power for height-standardisation of childhood weight, fat mass and fat-free mass across the obesity epidemic. [PDF]

Int J Obes (Lond)
Hudda MT, Aarestrup J, Owen CG, Baker JL, Whincup PH.   +4 more
europepmc   +1 more source

Relationship between fat-free mass index and nutrient intake in protein supplement user among Japanese collegiate soccer athletes. [PDF]

Phys Act Nutr
Takahashi R, Kobayashi Y, Fujii T, Kuwabara S, Segawa-Yoshimoto Y, Aoi W, Kuwahata M.   +6 more
europepmc   +1 more source

Fat-Free Mass Index in a Large Sample of Collegiate American Football Athletes. [PDF]

Int J Exerc Sci
Fields JB, Jones MT, Kuhlman NM, Magee MK, Feit A, Jagim AR.   +5 more
europepmc   +1 more source