Results 181 to 190 of about 588,469 (281)

Non-Traumatic Fat Embolism Syndrome in Sickle Cell Disease Complicated by Bone Marrow Necrosis Successfully Treated with Therapeutic Plasma Exchange: A Case Report. [PDF]

J Blood Med
Alsahman Ii LA, Alnemer BA, A Al Dawood SA, Alzaher MA, Al-Mutawa AHA.   +4 more
europepmc   +1 more source

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, Volume 13, Issue 49, 3 September 2026.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai, Keyu Wang, Jiali Fang, Shaorui Jia, Yansong Shi, Wanfeng Gao, Xinpeng Liu, Jiaqiang Li, Zenghui Cui, Yazhi Qian, Xiaosu Chen, Dan Ding, Xuetao Cao   +12 more
wiley   +1 more source

Fulminant cerebral fat embolism syndrome initially sparing the lungs after long-bone fractures: a case report of refractory status epilepticus. [PDF]

Front Med (Lausanne)
Lan J, Li X, Jian X, Zhong Q, Zhang X, Zheng C.   +5 more
europepmc   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, Volume 13, Issue 51, 14 September 2026.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Cerebral fat embolism syndrome in sickle cell disease: a case highlighting the predominance of susceptibility-weighted imaging findings and literature review. [PDF]

Radiol Case Rep
Failla G, Tiralongo F, Di Grigoli P, Falsaperla D, Inì C, Grippaldi D, Farina R, Messina G, David E, Foti PV, Palmucci S, Basile A.   +11 more
europepmc   +1 more source

Human Urine Stem Cells Alleviate Pulmonary Fibrosis via Inhibiting Macrophage‐Myofibroblast Transition

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Therapeutic role and mechanism of human urine stem cells (hUSCs) in pulmonary fibrosis. hUSCs alleviated pulmonary fibrosis by selectively inhibiting macrophage‐myofibroblast transition (MMT) in two ways: on one hand, hUSCs inhibited mitochondrial reactive oxygen species (mtROS) production and apoptosis/senescence of epithelial cells in pulmonary ...
Zhou‐Hang Zhang, Guan‐Lin Guo, Xiao‐Hui Guan, Min Hu, Qi‐Ming Huang, Ding‐Wen Guo, Hao‐Cheng Gu, You‐Qiong Zhuo, Ning Li, Hong‐Bo Xin, Ke‐Yu Deng   +10 more
wiley   +1 more source

Progress in Synthesis and Pharmacology of Telmisartan

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Telmisartan is a benzimidazole derivative and a well‐known drug to treat hypertension. This review provides synthesis and understanding of telmisartan as an antihypertensive drug through two mechanisms of actions: RAAS inhibitor and PPARγ receptor. Effective repurposing of this drug for various diseases like chronic kidney illness, diabetes, fatty ...
Megha, Richa Srivastava, Ram Singh
wiley   +1 more source

Impact of dexamethasone treatment on hematological indicators in patients with fat embolism syndrome. [PDF]

Eur J Med Res
Liu Y, Gao Q, Zhou F, Xiang G, Chen M, Shi P.   +5 more
europepmc   +1 more source

Timely Extracorporeal Cardiopulmonary Resuscitation for Intraoperative Cardiac Arrest Caused by Suspected Bone Cement Implantation Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Bone cement implantation syndrome should be suspected in patients with sudden circulatory collapse during cemented orthopedic surgery. Prompt recognition and timely extracorporeal cardiopulmonary resuscitation may improve neurological outcomes in carefully selected patients.
Yuta Kikuchi, Takashi Uchiyama, Hidehiko Nakamura   +2 more
wiley   +1 more source

TTP‐Like Syndrome and Subsequent Non‐Aneurysmal Subarachnoid Hemorrhage in HbSC Disease: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Sickle cell disease (SCD) with hemoglobin‐ (Hb‐) SC genotype is often considered a milder SCD variant, yet life‐threatening complications can occur. A 26‐year‐old man with HbSC disease presented with an infection triggered vaso‐occlusive crisis (VOC), acute chest syndrome (ACS), severe thrombocytopenia, Coombs‐negative hemolysis with ...
Benjamin Vieten, Jan Vorwerk, Jan Morf, Alice Dauth, Stefan Sondermann, Peter Schramm, Tobias Graf, Nikolas von Bubnoff, Lorenz Oelschläger, Cyrus Khandanpour   +9 more
wiley   +1 more source